Application of optical coherence tomography angiography in evaluation of the early macular retinal microcirculation in diabetics

doi:10.3877/cma.j.issn.2095-2007.2019.03.011

Abstract

Abstract:

Diabetic retinopathy is a series of lesions caused by microvascular damage of the retina, which is also the main cause of blindness in most patients. Abnormal insulin metabolism changes the ocular tissue, nerve and vascular microcirculation in diabetics, resulting in different degrees of visual impairment. The clinical manifestations of diabetics are bleeding spots, aneurysms, intraretinal microvascular abnormalities, and macular edema, etc. At present, fluorescein fundus angiography is the main clinical examination for the early macular retinal microcirculation in diabetics, which is regarded as "gold standard" . However, it is obviously traumatic and relatively time-consuming, leading to the poor compliance and poor tolerance for patients. Optical coherence tomography angiography is a novel, non-invasive angiography technique, but has few applications in the early detection of macular retinal microcirculation in diabetics. In this paper, the effect of early macular retinal microcirculation on the retina of diabetics was analyzed, and the application progress of optical coherence tomography angiography in the evaluation of early macular retinal microcirculation in diabetics was reviewed.

Key words: Diabetic retinopathy, Macular area, Retinal microcirculation, Optical coherence tomography angiography

Xinge Li, Xuchen Ding, Guodan Liu. Application of optical coherence tomography angiography in evaluation of the early macular retinal microcirculation in diabetics[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2019, 09(03): 187-192.

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