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中华眼科医学杂志(电子版) ›› 2025, Vol. 15 ›› Issue (06) : 321 -326. doi: 10.3877/cma.j.issn.2095-2007.2025.06.001

述评

重视近视防控中风险预测、前沿技术整合及个体化诊疗策略的构建
罗怡凡1, 杜永乐2, 柯碧莲3,†()   
  1. 1200025　上海交通大学医学院2025级博士研究生
    2200025　上海交通大学医学院2025级硕士研究生
    3200127　上海交通大学医学院附属仁济医院眼科
  • 收稿日期:2025-11-24 出版日期:2025-12-28
  • 通信作者: 柯碧莲
  • 基金资助:
    国家重点研发计划项目(2024YFC2510802); 国家自然科学基金项目(82371092)

Pay attention to the precise prediction of myopia onset and development, integration of cutting-edge technologies, and construction of individualized diagnosis and treatment strategies

Yifan Luo1, Yongle Du2, Bilian Ke3,†()   

  1. 1PhD student of 2025 at Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    2Master′s student of 2025 at the School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China
    3Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital Ophthalmology, Shanghai 200001, China
  • Received:2025-11-24 Published:2025-12-28
  • Corresponding author: Bilian Ke
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引用本文：

罗怡凡, 杜永乐, 柯碧莲. 重视近视防控中风险预测、前沿技术整合及个体化诊疗策略的构建[J/OL]. 中华眼科医学杂志(电子版), 2025, 15(06): 321-326.

Yifan Luo, Yongle Du, Bilian Ke. Pay attention to the precise prediction of myopia onset and development, integration of cutting-edge technologies, and construction of individualized diagnosis and treatment strategies[J/OL]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2025, 15(06): 321-326.

目前，近视防控在临床上的关注点已从单一的屈光矫正转向延缓眼轴病理性增长及预防高度近视导致的并发症。现有的治疗手段存在指标的滞后性、干预方式的趋同化尤其缺乏针对全生命周期的分级管理机制；对于眼轴与角膜曲率半径比值(AL/CR)、脉络膜微循环参数等新型近视生物标志物、重复低剂量红光照射以及联合疗法等近视管理方案的出现，制定系统化、个体化近视防控体系迫在眉睫。本文中笔者就近视早期预测模型的建立、防控新技术适应证的选择及"阶梯式"个体化诊疗策略的设计等三方面进行评述，期望能有益于促进近视防控向精准医疗迈进。

关键词: 近视, 近视防控, 精准预测, 脉络膜血流, 重复低强度红光照射

At present, the focus of myopia prevention and control in clinical practice has shifted from single refractive correction to delaying pathological axial growth and preventing complications caused by high myopia. The existing treatment methods have lagging indicators, homogenization of intervention methods, and a lack of hierarchical management mechanisms for the entire life cycle; With the emergence of new myopia biomarkers such as the ratio of axial curvature to corneal curvature radius (AL/CR), choroidal microcirculation parameters, repeated low-dose red light irradiation, and combination therapy for myopia management, it is urgent to develop a systematic and personalized myopia prevention and control system. The establishment of an early prediction model for myopia, the selection of indications for new prevention and control technologies, and the design of a " tiered" personalized diagnosis and treatment strategy were reviewed, with the hope of promoting myopia prevention and control towards precision medicine.

Key words: Myopia, Myopia prevention, Precise prediction, Choroidal blood flow, Repeated low-level red-light therapy
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