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中华眼科医学杂志(电子版) ›› 2025, Vol. 15 ›› Issue (05) : 263 -267. doi: 10.3877/cma.j.issn.2095-2007.2025.05.002

论著

周边部视网膜裂孔合并黄斑裂孔性视网膜脱离的临床研究
王聪, 贾力蕴, 曹绪胜, 周海英, 周金琼, 莫宾, 王红, 马凯, 张永鹏()   
  1. 100730 首都医科大学附属北京同仁医院 北京同仁眼科中心 眼科学与视觉科学北京市重点实验室
  • 收稿日期:2025-09-12 出版日期:2025-10-28
  • 通信作者: 张永鹏
  • 基金资助:
    北京市自然科学基金项目(7212016)

The clinical characteristics of rhegmatogenous retinal detachments with both peripheral retinal breaks and macular holes

Cong Wang, Liyun Jia, Xusheng Cao, Haiying Zhou, Jinqiong Zhou, Bin Mo, Hong Wang, Kai Ma, Yongpeng Zhang()   

  1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology & Visual Science, Beijing 100730, China
  • Received:2025-09-12 Published:2025-10-28
  • Corresponding author: Yongpeng Zhang
引用本文:

王聪, 贾力蕴, 曹绪胜, 周海英, 周金琼, 莫宾, 王红, 马凯, 张永鹏. 周边部视网膜裂孔合并黄斑裂孔性视网膜脱离的临床研究[J/OL]. 中华眼科医学杂志(电子版), 2025, 15(05): 263-267.

Cong Wang, Liyun Jia, Xusheng Cao, Haiying Zhou, Jinqiong Zhou, Bin Mo, Hong Wang, Kai Ma, Yongpeng Zhang. The clinical characteristics of rhegmatogenous retinal detachments with both peripheral retinal breaks and macular holes[J/OL]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2025, 15(05): 263-267.

目的

探讨周边部视网膜裂孔合并黄斑裂孔(MH)性视网膜脱离的临床特征、诊疗方法及预后。

方法

收集2020年11月至2023年10月于首都医科大学附属北京同仁医院眼科中心诊断为周边部视网膜裂孔合并MH性视网膜脱离的患者20例(20只眼)进行研究。其中,男性11例(11只眼),女性9例(9只眼);年龄30~67岁,平均年龄(51.8±10.5)岁。询问并记录患者病史,常规检查手术前和术后1个月、3个月及1年随访时患眼最佳矫正视力、眼前节及眼底情况,病例资料采用例数(眼数)和百分比进行描述。

结果

全部周边部视网膜裂孔患者20例(20只眼)中,术前发现MH和术中发现MH的患者分别为13例(13只眼)和7例(7只眼),分别占65%(13/20)和35%(7/20);行25G/23G微创玻璃体切除术和初次行巩膜扣带手术术后发现遗漏MH再行25G微创玻璃体切除术者分别为18例(18只眼)和2例(2只眼),分别占90%(18/20)和10%(2/20);术中填充硅油或全氟丙烷者分别为17例(17只眼)和3例(3只眼),分别占85%(17/20)和15%(3/20);1次手术和2次手术视网膜脱离复位的患者分别为19例(19只眼)和1例(1只眼),分别占95%(19/20)和5%(1/20);术后MH闭合和MH未闭合者分别为18例(18只眼)和2例(2只眼),分别占90%(18/20)和10%(2/20);术后视力提高、视力不变及视力下降者分别为18例(18只眼)、1例(1只眼)及1例(1只眼),分别占90%(18/20)、5%(1/20)及5%(1/20)。

结论

周边部视网膜裂孔视网膜脱离患者病情发展过程中可并发MH,并发MH的时机可发生在初诊时、待入院时、待手术时及手术中。因此,不可仅凭初诊为准还应关注待入院时、待手术时及手术中是否发生MH,避免漏诊漏治。玻璃体切除联合惰性气体或硅油填充,是治疗周边裂孔视网膜脱离合并MH的有效治疗手段。

Objective

To explore the clinical characteristics, diagnosis and treatment methods, and prognosis of retinal detachment caused by peripheral retinal holes combined with macular holes (MH).

Methods

A total of 20 patients (20 eyes) diagnosed with peripheral retinal tears combined with MH retinal detachment were collected at the Ophthalmic Center of Beijing Tongren Hospital affiliated to Capital Medical University from November 2020 to October 2023. Among them, there were 11 males (11 eyes) and 9 females (9 eyes) with an average age (51.8±10.5) years old (ranging from 30 to 67 years old). The patient′s medical history, conduct routine examinations before surgery and at 1 month, 3 months, and 1 year follow-up after surgery were recorded to determine the best corrected visual acuity, anterior segment, and fundus condition of the affected eye. The case data was described using the number of cases (eyes) and percentage.

Results

Among the 20 patients (20 eyes) with peripheral retinal holes, 13 (13 eyes) were diagnosed with MH before surgery and 7 (7 eyes) were diagnosed with MH during surgery, accounting for 65% (13/20) and 35% (7/20), respectively. After undergoing 25G/23G minimally invasive vitrectomy and initial scleral buckle surgery, 18 cases (18 eyes) and 2 cases (2 eyes) were found to have missed MH and underwent 25G minimally invasive vitrectomy again, accounting for 90% (18/20) and 10% (2/20), respectively; 17 cases (17 eyes) and 3 cases (3 eyes) were filled with silicone oil or perfluoropropane during surgery, accounting for 85% (17/20) and 15% (3/20), respectively; 19 cases (19 eyes) and 1 case (1 eye) of retinal detachment were treated with one surgery and two surgeries, respectively, accounting for 95% (19/20) and 5% (1/20), respectively. There were 18 cases (18 eyes) and 2 cases (2 eyes) of postoperative MH closure and MH non closure, accounting for 90% (18/20) and 10% (2/20), respectively; The postoperative visual acuity improved, remained unchanged, and decreased in 18 cases (18 eyes), 1 case (1 eye), and 1 case (1 eye), respectively, accounting for 90% (18/20), 5% (1/20), and 5% (1/20), respectively.

Conclusions

Patients with peripheral retinal tears and retinal detachment may develop MH during the course of their condition, which can occur at the time of initial diagnosis, admission, surgery, and during the operation. Therefore, it is not enough to rely solely on initial diagnosis. Attention should also be paid to whether MH occurs during hospitalization, surgery, and surgery to avoid missed diagnosis and treatment. Vitrectomy combined with inert gas or silicone oil filling is an effective treatment for peripheral retinal detachment with MH.

图2 病例3患者术后超广角激光扫描眼底成像和相干光断层扫描图像 图示患者左眼行玻璃体切除、内界膜剥除联合硅油填充术,硅油取出术后左眼视网膜复位。其中,图2A示术后超广角激光扫描眼底成像可见左眼视网膜复位;图2B示术后相干光断层扫描显示患眼黄斑裂孔闭合,视网膜复位;图2C示术后相干光断层扫描其他角度扫描亦显示患眼黄斑裂孔闭合,视网膜复位,最佳矫正视力0.8
表1 全部周边部视网膜裂孔视网膜脱离并发黄斑裂孔患者20例(20只眼)的情况
病例编号 性别 年龄 眼别 眼底情况 术前BCVA 术后BCVA 术后MH闭合 术后视网膜复位
1 57 左眼 下方周边部圆孔及马蹄形裂孔,合并MH 0.05 0.3
2 63 右眼 上方长条形变性区两端裂孔,合并MH 手动 0.1
3 44 左眼 先发生鼻下方大马蹄形裂孔,其后发生MH 手动 0.8
4 43 左眼 上方周边马蹄孔,下方周边圆孔,MH合并脉络膜脱离 0.1 0.05
5 34 右眼 上方周边变性区两端裂孔,下方多发裂孔,合并MH 手动 0.4
6 64 右眼 上方变性区一端马蹄形裂孔,合并MH 光感 0.05
7 38 右眼 颞侧周边部巨大视网膜裂孔,合并MH 手动 0.02
8 52 右眼 上方变性区一端马蹄形裂孔,合并MH 手动 0.2
9 59 左眼 周边变性区多发裂孔,合并MH,合并脉络膜脱离 0.01 0.05
10 30 右眼 上方睫状上皮脱离,下方多发裂孔,合并MH 手动 0.02
11 53 左眼 颞上周边部视网膜裂孔,合并MH,合并脉络膜脱离 0.06 0.15
12 59 左眼 先发生颞上马蹄形裂孔,其后发生MH 0.05 0.1
13 55 右眼 周边变性区两个裂孔,合并MH 0.01 0.3
14 49 左眼 颞上,颞下长条形变性区一端撕裂孔,合并MH 指数 0.05
15 65 右眼 颞侧周边部视网膜裂孔,合并MH 0.02 0.02
16 63 右眼 颞侧周边多个马蹄形裂孔,下方多个干孔,合并MH 手动 0.3
17 67 左眼 颞上马蹄形裂孔,合并MH 0.01 0.1
18 51 左眼 颞上条形变性区内裂孔,合并MH 0.05 0.2
19 42 左眼 颞上锯齿缘离断,鼻下裂孔,MH合并脉络膜脱离 0.07 0.1
20 47 右眼 颞上马蹄形裂孔,合并MH 0.06 0.12
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