The aim of this study was to compare and analyze the change trend and axial movement of effective lens position (ELP) in cataract patients after implantation of 3 multifocal intraocular lens by using Swept-sourceoptial coherence tomography (SS-OCT).

79 Age-related cataract patients (92 eyes) admitted to WeiFang Eye Hospital from March to December 2018 were divided into three groups: Lisa group, Restor group and Oculentis group, which were implanted by AT Lisa tri839MP, AcrySof Restor and Oculentis LS-313 intraocular lens, respectively. All patients received femtosecond laser-assisted cataract surgery by the same operator. The ELP measurements by IOLMaster700 were taken after operation for 1 week, 1 and 3 months. The ELP_RMS was defined as the root mean square (RMS) of the change in ELP at different follow-up timepoint. The number of cases and percentage were used to describe the gender of three groups before operation, and Chi-square test was used for comparison between groups. The age, anterior chamber depth, the lens thickness and the degrees of intraocular among three groups were represented by Mean±SD; single factor analysis of variance was used for comparison between groups. Three groups were compared by two factors repeated measurement variance analysis at different time points. When the difference was statistically significant, SNK method was further used for comparison.

There was non-significant different in gender among of three groups (χ²=0.96, P>0.05). There was non-significant different in age, anterior chamber depth, lens thickness and intraocular lens diopter among of three groups (F=1.38, 0.16, 2.40, 0.35, 0.89; P>0.05). The mean ELP in Lisa group after operation for 1 week, 1 month and 3 month was (4.84±0.14) mm, ( 4.95±0.17) mm and (4.97±0.17) mm, respectively. There was statistically significant different among of them (F=2.29, P<0.05). However, there was no significant changes in the mean ELP between 1 month and 3 months postoperatively (F=0.38, 0.37; P>0.05). The mean ELP in Restor group after operation for 1 week, 1 month and 3 month was (4.94±0.25) mm, (4.95±0.28) mm and (4.92±0.27) mm. The Restor group showed no significant changes in the mean ELP between 1 week and 1 month postoperatively (F=0.13, P>0.05), 1 month and 3 months postoperatively (F=0.37, P>0.05). The mean ELP in Oculentis group after operation for 1 week, 1 month and 3 months was (4.72±0.25) mm, (4.80±0.23) mm and (4.80±0.22) mm. There was significant different in the mean ELP between 1 week and 1 month postoperatively (F=2.35, P<0.05); non-significant different between 1 month and 3 months postoperatively (F=0.08, P>0.05). The difference in the mean ELP among three groups at different periods (F=1.56, 1.78, 1.45; P>0.05), which could not be considered statistically significant. The ELP_RMS of Lisa group, Restor group and Oculentis group was (0.08±0.07) mm, (0.04±0.04) mm and (0.06±0.06) mm, respectively, showing non-statistical significant difference among three groups (F=2.16, P>0.05).

The time required for three different designs of intraocular lens to reach stable state in the capsule bag was different. For example, AcrySof Restor required for a week, AT Lisa tri 839MP and Oculentis LS-313 for a month. The root mean of ELP changes could reflect the amount of axial movement of the intraocular lens. Swept-source optical coherence tomography is an effective method to evaluate the effective position and axial movement after intraocular lens implantation.