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中华眼科医学杂志(电子版) ›› 2026, Vol. 16 ›› Issue (01) : 43 -47. doi: 10.3877/cma.j.issn.2095-2007.2026.01.008

综述

过敏性炎症与近视眼发生及发展免疫学关联的研究进展
关文英1,2, 刘祖国2,()   
  1. 1010050 呼和浩特,内蒙古医科大学附属医院眼视光中心
    2361102 厦门大学附属厦门眼科中心 厦门大学附属翔安医院 厦门大学眼科研究所
  • 收稿日期:2025-12-24 出版日期:2026-02-28
  • 通信作者: 刘祖国
  • 基金资助:
    国家自然科学基金资助项目(82271054)

The advances on immunological links between allergic inflammation and myopia development

Wenying Guan1,2, Zuguo Liu2,()   

  1. 1Optometry Center, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China
    2Affiliated Xiamen Eye Center of Xiamen University, Xiang′an Affiliated Hospital of Xiamen University, Eye Institute of Xiamen University, Xiamen 361102, China
  • Received:2025-12-24 Published:2026-02-28
  • Corresponding author: Zuguo Liu
引用本文:

关文英, 刘祖国. 过敏性炎症与近视眼发生及发展免疫学关联的研究进展[J/OL]. 中华眼科医学杂志(电子版), 2026, 16(01): 43-47.

Wenying Guan, Zuguo Liu. The advances on immunological links between allergic inflammation and myopia development[J/OL]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2026, 16(01): 43-47.

近视眼的发生与发展主要受环境和遗传因素调控,但免疫性及过敏性炎症亦可能在近视眼眼轴增长中发挥重要的调节作用。过敏性疾病与近视眼是影响全球近半数人群的两大疾病。关注二者的共病关系对近视眼的防控具有重要意义。本文中笔者就过敏性免疫失衡、眼部过敏性疾病、眼部免疫组成以及免疫炎症与近视眼关系的研究进展进行综述,旨在从免疫调控和靶向干预角度探讨近视眼防控与治疗。

The onset and progression of myopia to be predominantly was regulated by environmental and genetic factors. However, in recent years, accumulating clinical and basic research evidence has suggested that immune-mediated and allergic inflammation may play a non-negligible regulatory role in axial elongation during myopia development. The comorbidity between two highly prevalent diseases that affect nearly half of the global population. Paying attention the associations between allergic diseases and myopia was meaningful. The current research progress on the relationship between allergic immune imbalance, ocular allergic diseases, the immune composition of the eye, immune inflammation and myopia were systematically reviewed and analyzed, with the aim of providing potential insights for both clinical and basic research on myopia prevention and treatment from the perspectives of immune regulation and targeted intervention.

图1 过敏与近视眼关系示意图
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