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中华眼科医学杂志(电子版) ›› 2025, Vol. 15 ›› Issue (05) : 309 -313. doi: 10.3877/cma.j.issn.2095-2007.2025.05.010

综述

角膜生物力学参数在白内障诊治中应用的研究进展
廉志恒, 胡柯()   
  1. 400016 重庆医科大学附属第一医院眼科 重庆市重大致盲眼病防治重点实验室 重庆市眼科研究所 国家临床眼科研究中心重庆分部(市立)
  • 收稿日期:2025-09-18 出版日期:2025-10-28
  • 通信作者: 胡柯
  • 基金资助:
    重庆市科卫联合医学科研项目重点项目(2024ZDXM033)

Advances on the corneal biomechanics in cataract surgery

Zhiheng Lian, Ke Hu()   

  1. The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, Chongqing 400016, China
  • Received:2025-09-18 Published:2025-10-28
  • Corresponding author: Ke Hu
引用本文:

廉志恒, 胡柯. 角膜生物力学参数在白内障诊治中应用的研究进展[J/OL]. 中华眼科医学杂志(电子版), 2025, 15(05): 309-313.

Zhiheng Lian, Ke Hu. Advances on the corneal biomechanics in cataract surgery[J/OL]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2025, 15(05): 309-313.

角膜生物力学参数能够直接反映角膜的弹性和硬度等结构变化,对白内障手术诊疗具有重要参考价值。在白内障相关手术中,手术切口的大小、位置及制作切口的方式等也会直接引起角膜生物力学参数的改变,从而影响术后视力恢复。尤其是在合并角膜病变、异常眼轴及青光眼等手术高危患者中,将角膜生物力学参数用于评估手术效果及并发症风险,有助于制定个性化手术方案,实现术后精准监测。本文中笔者梳理角膜生物力学参数在白内障诊治在术前评估及术后随访中的价值,探讨不同手术方式角膜对生物力学造成的影响及术后预后的关联,分析当前研究存在的局限与不足,为后续临床研究方向及诊疗方案优化提供参考,推动白内障诊疗向更精准且个性化的方向发展。

Corneal biomechanics can directly reflect structural changes of the cornea, including indicators such as elasticity and hardness, and has an important reference value for the diagnosis and treatment of cataract surgery. In cataract-related surgeries, factors such as the size and location of the surgical incision, as well as the method of incision creation, can also directly affect changes in corneal biomechanical parameters, thereby influencing the recovery of postoperative visual acuity. Especially in high-risk surgical patients, such as those with concurrent corneal lesions, abnormal axial length, or glaucoma, the application of corneal biomechanical parameters to evaluate surgical effects and the risk of complications helps formulate personalized surgical plans and achieve precise postoperative monitoring. To sort out its value in preoperative evaluation and postoperative follow-up, explore the impact of different surgical methods on biomechanics and its correlation with postoperative prognosis, analyze the limitations and deficiencies of current studies, was included in this paper, which to provide references for the direction of subsequent clinical research and the optimization of diagnosis and treatment plans, and promotes the development of cataract diagnosis and treatment towards a more precise and personalized direction.

图1 角膜生物力学在白内障合并复杂眼部疾病中临床应用的整合示意图
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