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中华眼科医学杂志(电子版) ›› 2017, Vol. 07 ›› Issue (04) : 177 -183. doi: 10.3877/cma.j.issn.2095-2007.2017.04.006

所属专题: 文献

综述

内界膜剥除术在糖尿病性黄斑水肿中的应用进展
孙艺梦1, 马凯1,()   
  1. 1. 100730 首都医科大学附属北京同仁医院北京同仁眼科中心 北京市眼科学与视觉科学重点实验室
  • 收稿日期:2017-07-05 出版日期:2017-08-28
  • 通信作者: 马凯
  • 基金资助:
    国家自然科学基金(30772378)

Application of internal limiting membrane peeling for the treatment of diabetic macular edema

Yimeng Sun1, Kai Ma1,()   

  1. 1. Beijing Tongren Eye Center, Beijing Tongren Hospital of Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, Beijing 100730, China
  • Received:2017-07-05 Published:2017-08-28
  • Corresponding author: Kai Ma
  • About author:
    Corresponding author: Ma Kai, Email:
引用本文:

孙艺梦, 马凯. 内界膜剥除术在糖尿病性黄斑水肿中的应用进展[J]. 中华眼科医学杂志(电子版), 2017, 07(04): 177-183.

Yimeng Sun, Kai Ma. Application of internal limiting membrane peeling for the treatment of diabetic macular edema[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2017, 07(04): 177-183.

内界膜作为视网膜的内层结构,与玻璃体紧密粘附,并且作为玻璃体和视网膜的支架,有着重要的生物力学和生理学作用。内界膜可产生切向牵拉力,同时也是胶质细胞增殖的场所,它在糖尿病性黄斑水肿(DME)的发生与发展中扮演着重要角色。因此,经睫状体平坦部行玻璃体切除术(PPV)联合内界膜剥除可能成为治疗牵拉性或非牵拉性黄斑水肿的一种手术方式,对于弥漫性难治性的黄斑水肿来说,它可能成为一种替代疗法。本文中笔者总结了内界膜在DME发病机制中的重要作用,回顾了DME的治疗现状和进展,并对DME内界膜剥除术的术后结构、功能预后、优势、副作用及最佳手术时机进行综述。

The internal limiting membrane as the inner structure of retina closely attached to vitreous, serves as an interface between the vitreous and retina with important biomechanical and physiological role. internal limiting membrane contributes to tangential traction and acts as a platform on which glial cells proliferate. internal limiting membrane plays a crucial part in the occurrence and development of Diabetic Macular Edema(DME). Thus, pars plana vitrectomy(PPV) with internal limiting membrane peeling could be an effective surgical treatment for tractional or non-tractional DME and an alternative therapy for diffuse and refractory DME.We highlight the internal limiting membrane’s role in DME pathogenesis and review the present situation and advances in treatment of DME.We also show the anatomical and functional findings after internal limiting membrane peeling in DME patients and discuss the benifical and adverse effects associated with internal limiting membrane peeling and optimal time for operation.

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