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中华眼科医学杂志(电子版) ›› 2017, Vol. 07 ›› Issue (04) : 184 -192. doi: 10.3877/cma.j.issn.2095-2007.2017.04.007

所属专题: 文献

综述

角膜碱性烧伤药物治疗的现状与研究进展
王健1, 解正高1,(), 杜伟1   
  1. 1. 225001 江苏省苏北人民医院眼科,扬州大学医学院
  • 收稿日期:2017-03-19 出版日期:2017-08-28
  • 通信作者: 解正高
  • 基金资助:
    国家自然科学基金青年基金(81500759)

Current status and progress in the treatment of corneal alkali burn

Jian Wang1, Zhenggao Xie1,(), Wei Du1   

  1. 1. Department of Ophthalmology, Subei People′s Hospital of Jiangsu province, Medical College of Yangzhou University. Yangzhou 225001, China
  • Received:2017-03-19 Published:2017-08-28
  • Corresponding author: Zhenggao Xie
  • About author:
    Corresponding author: Xie Zhenggao, Email:
引用本文:

王健, 解正高, 杜伟. 角膜碱性烧伤药物治疗的现状与研究进展[J]. 中华眼科医学杂志(电子版), 2017, 07(04): 184-192.

Jian Wang, Zhenggao Xie, Wei Du. Current status and progress in the treatment of corneal alkali burn[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2017, 07(04): 184-192.

眼化学伤,特别是碱性烧伤是临床复杂而难以治愈的眼部疾病之一。碱性物质与眼部组织接触后,会形成可溶于水的碱-变性蛋白复合物,该物质皂化脂肪组织,从而引发组织的液化性坏死,使碱性物质迅速向四周及深部组织扩散,腐蚀眼内组织,造成角膜变性、坏死、穿孔及新生血管的形成,严重威胁患者的视力。近年来,随着基础医学的发展,角膜碱性烧伤的药物治疗方法也取得了进一步地发展。本文中,笔者就近年来角膜碱性烧伤的药物治疗方法进行简要综述。

Chemical burn of eyes, especially alkali burn, is one of the most complicated and difficult diseases to cure. Alkaline contact with tissue results in the formation of water soluble alkali denatured protein complexes, saponified adipose tissue, liquefaction necrosis of tissue occurred, cause the alkaline substance to diffuse rapidly to the surrounding and deep tissues, erosion of intraocular tissue, resulting in corneal degeneration, necrosis, perforation and neovascularization, severe threat to patient vision. In recent years, with the development of Basic Medicine, further progress has been made in the treatment of alkali burn. In this paper, we reviewed the recent advances in the treatment of corneal alkaline burn.

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