The aim of this study was to observe the inflammatory reactionafter phacoemulsification combined with implantation of heparin surface-modified intraocular lens.

From June 2019 to October 2019, 62 cases (82 eyes) of age-related cataract with phacoemulsification and intraocular lens implantation were studied in the Department of ophthalmology, Wei Fang Eye Hospital.Among of them, there were 27 males (33 eyes), 35 females (49 eyes), aged 40 to 85 years-old with an average age of ( 65.6±10.0) years-old. According to the intraocular lens type, the patients included in the study were divided into three groups: AQBH group, iSert group and LUCIA group.All patients of three groups received intraoperative implantation of correspondingintraocular lens (IOL) in the capsule bag. After one day, three days, one week, one month and three months operation, the subjects were follwed up to record anterior chamber flare, respectively. Three groups were compared by two factors repeated measurement variance analysis at different time points. When the difference was statistically significant, SNK method was further used for comparison.

One day after operation, the anterior chamber flare of the AQBH group, iSertgroup, LUCIA group were (10.79±0.97) p/ms, (15.37±1.00) p/ms and (10.07±0.98) p/ms, respectively. There was significant difference between the LUCIA group andthe iSert group and between the AQBH group and the iSert group(t=-3.78, -3.29; P<0.05), There was no significant difference among other groups (t=-3.29, P>0.05). Three days after operation, the anterior chamber flare of the AQBH group, iSertgroup, LUCIAgroup were (14.24±0.97) p/ms, (10.14±1.00) p/ms and (7.29±0.98) p/ms, respectively. There was significant difference between the LUCIA group and the iSert group (t=-2.03, P<0.05) . There was no significant difference among other groups(t=-1.38, -0.68, P>0.05) . One month after operation, the anterior chamber flare of the AQBH group, iSert group and LUCIA group were (9.19±0.97) p/ms, (13.17±1.00) p/ms and (7.70±0.98) p/ms, respectively. There was significant difference between the LUCIA group and the iSert group and between the AQBH group and the iSert group(t=-3.90, -2.86; P<0.05). There was no significant difference among other groups(t=-1.07, P>0.05). Three months after operation, the anterior chamber flare of the AQBH group, iSert group and LUCIA group were (7.43±0.97) p/ms, (8.02±1.00) p/ms and (5.93±0.98) p/ms, respectively. There was no significant difference among three groups(t=-1.09, -1.49, -0.42; P>0.05).

Compared with the iSert group, the values of anterior chamber flare of the LUCIA group were lower. That data of the third day after the operation in LUCIA group were slightly lower than those in AQBH group. However, only the difference of the third day was shown statistically significant. There are no significant difference among three groups after operation for three months.