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Chinese Journal of Ophthalmologic Medicine(Electronic Edition) ›› 2023, Vol. 13 ›› Issue (02): 94-98. doi: 10.3877/cma.j.issn.2095-2007.2023.02.006

• Review • Previous Articles     Next Articles

Research progress of non-coding RNA related to cataract

Rui Fang, Xudong Song()   

  1. Scientific doctoral degree 2021, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
    Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Vision Sciences, Beijing 100730, China
  • Received:2022-09-01 Online:2023-04-28 Published:2023-08-14
  • Contact: Xudong Song

Abstract:

Ribonucleic acid (RNA) that does not encode proteins is called non coding RNA. Among them, regulatory non coding RNA mainly includes microRNA (miRNA), long chain non coding RNA (lncRNA) and circular RNA (circRNA). Non coding RNA plays a crucial role in various biological processes such as cell growth, proliferation, differentiation, apoptosis, and oxidative stress. In recent years, it has been demonstrated that non coding RNA plays an important regulatory role in the occurrence and development of cataracts, and may become a promising new target for non-surgical treatment. In this paper, the research progress on non coding RNA and cataract in recent years both domestically and internationally were reviewed.

Key words: Non-coding RNA, MicroRNA, Long noncoding RNA, Circular RNA, Cataract

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