The aim of this study was to study the mid-term clinical outcomes of SBL-3 asymmetric segmented multifocal intraocular lens.

Prospective study. 59 subjects (87 eyes) in AIER Eye Hospital(Chengdu) diagnosed with aged related cataract from Jun 2016 to Jan 2018 were enrolled in this study. All subjects were follow-up from 3 to 12 months postoperatively. They were divided into two groups according to the type of intraocular lens implanted. Multi-focal group: 30 subjects (40 eyes) were implanted with SBL-3 Mf-IOL. Monofocal group: 29 subjects (47 eyes) were implanted with mono-focal IOL (Softec HD). The uncorrected distance VA (5 meters), intermediate VA (80 cm), near VA and spherical equivalent were measured at each visit. Visual function was evaluated by using the VF-14-CN questionnaire. Double-pass visual quality analysis system was used to evaluated the visual quality, including the Objective Scatter Index (OSI), Modulation transfer function cut off (MTF cutoff), strehl ratio (SR), contrast sensitive at 100%, 20%, 9% respectively and the pseudo-accommodation. Independent sample t test was used to compare the indices of patients in monofocal group and multifocal group, and paired t test was used to compare the indices before and after operation.

Distance VA of all subjects were improved dramatically after surgery (t=-13.382, -10.859; P<0.05). No significant statistical difference was found between multi-focal group and mono-focal group in spherical equivalent (t=1.370, P>0.05). Uncorrected distance VA in multi-focal group was (0.87±0.17) and in mono-focal group was (0.82±0.21), Corrected distance VA in multi-focal group was (0.91±0.13) and in mono-focal group was (0.91±0.14), but there were no statistical differences between two groups (t=-1.129, 0.081; P>0.05). Intermediate VA: Multi-focal group was (0.70±0.17), mono-focal group was (0.54±0.22), multi-focal group was better than mono-focal group (t=-3.888, P<0.05). Near VA: multi-focal group was (0.71±0.20), mono-focal group was (0.28±0.10), multi-focal group was better than mono-focal group (t=-12.340, P<0.05). In terms of VF-14 scale score, the former group (75.39±10.30) was significantly lower than the later group(97.50±4.50), and the difference was statistically significant (t=-9.837, P<0.05). As for reading glasses, 44 of 47 subjects (93.6%) need reading glasses for near vision in the mono-focal group, but only 2 of 40 (5%) need reading glasses in the multi-focal group. The difference was also statistically significant ( χ²=68.104, P<0.05). As for glare, 2 of 47 subjects (4.26%) of mono-focal group was reported glare compared to the multi-focal group (3 of 40 subjects). No statistical significance was found (χ²=0.035, P>0.05). MTF cutoff in mono-focal group (27.00±10.98)c/deg was better than in multi-focal group (24.17±7.68), but no significant statistical differences were found between two groups (t=1.398, P>0.05). OSI in mono-focal group (1.7±0.8) was better than in multi-focal group (2.0±0.7), but no significant statistical differences were found between two groups (t=-2.139, P>0.05). Significant statistical differences were found between two groups in SR (0.13±0.03), mono-focal group was (0.15±0.06), (t=2.130, P<0.05). The contrast sensitivity vision of mono-focal group was better than multi-focal at 100%, 20% and 9% contrast, but still no statistical difference was found. (t=1.545, 1.886, 1.968; P>0.05). In terms of pseudo-accommodation, multi-focal group (2.30±0.80) D was much higher than mono-focal group (1.60±0.70)D. (t=-3.600, P<0.05).

Compared to the traditional mono-focal IOL, the novel SBL-3 asymmetric segmented multifocal intraocular lens can provide better full range of clear vision and visual quality, which may help to achieve good patient postoperative satisfaction.