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中华眼科医学杂志(电子版) ›› 2021, Vol. 11 ›› Issue (01) : 48 -53. doi: 10.3877/cma.j.issn.2095-2007.2021.01.008

综述

圆锥角膜基质环植入术的研究进展
谢江淼1, 洪晶1,†()   
  1. 1. 100191　北京大学第三医院眼科
  • 收稿日期:2020-10-11 出版日期:2021-02-28
  • 通信作者: 洪晶
  • 基金资助:
    国家自然科学基金项目(81970768)

Advances on intrastromal corneal ring segments implantation

Jiangmiao Xie1, Jing Hong1,†()   

  1. 1. Ophthalmology Department, Peking University 3 Hospital, Beijing 100191, China
  • Received:2020-10-11 Published:2021-02-28
  • Corresponding author: Jing Hong
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谢江淼, 洪晶. 圆锥角膜基质环植入术的研究进展[J]. 中华眼科医学杂志(电子版), 2021, 11(01): 48-53.

Jiangmiao Xie, Jing Hong. Advances on intrastromal corneal ring segments implantation[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2021, 11(01): 48-53.

角膜基质环植入术(ICRS)是一种用于治疗轻中度圆锥角膜的手术方法。ICRS是通过植入基质环，使中央角膜扁平化，弧长缩短，角膜曲率半径增大，屈光力降低，从而改善角膜前突导致的轴性近视眼与不规则散光。ICRS具有微创性、安全性、有效性、可逆性且并发症少等优点，其中长期疗效较佳。本文中笔者就ICRS的发展史、适应症、手术方法、手术疗效的影响因素、术后处理及疗效的评估等方面进行阐述。

关键词: 圆锥角膜, 角膜基质环, 角膜基质环植入术, 疗效评价

Intrastromal corneal ring segments (ICRS) implantation is a surgical way to treat mild-to-moderate keratoconus. As the central cornea is relatively flattened after implantation, it serves an arc-shorted effect, causing the radius of corneal curvature shortened and the refraction decreased, which to improve the axial myopia and irregular astigmatism caused by cornea ectasia and protrusion. Meanwhile, it is minimal invasive, safe, effective and reversible and its long-term efficacy gradually gets admitted. ICRS implantation for its history, surgical steps, indications and outcomes in clinical realms were reviewed in this paper, which to provide some practical and useful information for clinical operation.

Key words: Keratoconus, Intrastromal corneal ring segments, ICRS implantation, Efficacy evaluation
图2 圆锥角膜的扩张分布图　图2A~图2D分别为全部扩张区域(0∶100%)、75%扩张区域(25%∶75%)、66%扩张区域位于角膜一侧(33%∶66%)及扩张区域在角膜两侧对称分布(50%∶50%)
图3 患者术后一年的眼前节照相与术后患者的相干光断层扫描成像　图3A白色箭头所指为360°圆锥角膜基质环；图3B示患者术后一年的裂隙灯检查成像；图3C示从角膜切面可见角膜基质环的横截面为三角形(白色箭头所示为植入的角膜基质环)
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