Comparision of corneal biometric measurements before refractive surgery between the MS-39 anterior segment analyzer and the Pentacam 3D anterior segment analyzer

doi:10.3877/cma.j.issn.2095-2007.2024.03.002

Abstract

Abstract:

Objective

To investigate the differences and similarities between MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer in corneal biometry before refractive surgery.

Methods

A total of 78 patients (156 eyes) scheduled for refractive surgery in the Refractive Surgery Center of Beijing Tongren Hospital Affiliated to Capital Medical University from May 2020 to July 2020 were collected. There were 22 males (44 eyes) and 56 females (112 eyes) with the average age of (29.5±6.1) years (ranging from 22 to 48 years). MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer were used to measure the corneal curvature (K1), corneal curvature (K2), corneal volume, anterior chamber depth (ACD), Kappa angle, corneal Q value, corneal spherical aberration and corneal high-order aberration. After examination, the patient′s age, intraocular pressure, sphericity and cylindricity conformed to the normal distribution, and were expressed as ±s. K1, K2, corneal volume, ACD, Kappa angle, corneal Q value, corneal spherical aberration and corneal higher-order aberration did not conform to normal distribution, and were described by median and interquartile distance. Wilcoxon signed rank test was used to analyze the difference of the two equipment detection indices, Spearman test was used to analyze the correlation, and Bland-Altman test was used to analyze the consistency.

Results

The corneal curvature K1 values of 78 patients (156 eyes) treated with MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer were 43.03 (40.49, 46.44) D and 42.08 (40.10, 42.05) D, respectively, with a statistically significant difference between them (Z=-8.56, P<0.05). The corneal curvature K2 measured by MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer were 44.37 (41.37, 48.89) D and 44.30 (41.20, 48.70) D, respectively, and the difference was statistically significant (Z=-4.50, P<0.05). The corneal volume measured by MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer were 56.20 (50.6, 63.8) mm³ and 59.70 (54.2, 67.6) mm^3, respectively, and the difference was statistically significant (Z=-10.87, P<0.05). The ACD measured by MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer were 3.77 (3.22, 4.50) mm and 3.71 (3.15, 4.45) mm, respectively, and the difference was statistically significant (Z=-7.56, P<0.05). The Kappa angle measured by MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer were -0.04 (-0.42, 0.41) ° and 0.18 (0.00, 0.42) ° respectively, and the difference was statistically significant (Z=-10.28, P<0.05). The corneal Q values measured by MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer were -0.16 (-0.46, 0.53) and -0.29 (-1.03, -0.01), respectively, and the difference was statistically significant (Z=-9.75, P<0.05). The corneal spherical aberration measured by MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer were 0.23 (0.02, 0.56) D and 0.15 (-0.13, 0.34) D, respectively, and the difference was statistically significant (Z=-9.50, P<0.05). The corneal high-order aberrations measured by MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer were 0.43 (-0.37, 1.16) D and 0.37 (0.23, 1.90) D, respectively, and the difference was statistically significant (Z=-6.76, P<0.05). The K1, K2, corneal volume, ACD measured by MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer were great highly correlated (r=0.97, 0.94, 0.95, 0.96; P<0.05). The corneal spherical aberration and corneal Q value weres highly correlated between two devices (r=0.67, 0.54; P<0.05). There was no correlation between Kappa angle and corneal high-order aberration (r=0.24, 0.30; P>0.05). The average values of K1, K2, ACD, Kappa angle, corneal Q value, corneal spherical aberration and corneal high-order aberration measured by Pentacam 3D anterior segment analyzer and MS-39 anterior segment analyzer (95% consistency limit interval) were 0.27 (-0.37~0.91) D, 0.19 (-0.80~1.19) D, 0.05 (-0.10~0.20) mm, -0.21 (-0.53~0.10)°, 0.13(-0.15 ~ 0.41), -3.30(-5.0 ~ -1.61)mm^3, 0.08(-0.08 ~ 0.24)D, 0.08(-0.32 ~ 0.47)D, respectively. There were 6.4%(10/156), 1.9%(3/156), 6.4%(10/156), 4.5%(7/156), 3.2%(5/156), 5.8%(9/156), 3.8%(6/156), 3.2%(5/156) located within the 95% consistency boundary interval, respectively.

Conclusions

There were differences in 8 indices detected by MS-39 anterior segment analyzer and Pentacam 3D anterior segment analyzer, but they had high correlation and consistency on the whole.

Key words: Corneal biometric measurement, MS-39 anterior segment analyzer, Pentacam 3D anterior segment analyzer

Jing Liu, Shanshan Wei, Yan Zheng, Li Zhang, Changbin Zhai. Comparision of corneal biometric measurements before refractive surgery between the MS-39 anterior segment analyzer and the Pentacam 3D anterior segment analyzer[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2024, 14(03): 134-139.

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References 20

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检查设备	眼数	平坦轴角膜曲率K1 (D)	陡峭轴角膜曲率K2 (D)	角膜体积(mm³)	前房深度(mm)
MS－39	156	43.03(40.49，－46.44)	44.37(41.37，－48.89)	56.20(50.6，－63.8)	3.77(3.22，－4.50)
Pentacam	156	42.08(40.10，－42.05)	44.30(41.20，－48.70)	59.70(54.2，－67.6)	3.71(3.15，－4.45)
Z值		－8.56^a	－4.50^a	－10.87^b	－7.56^a
P值		<0.05	<0.05	<0.05	<0.05
检查设备	眼数	Kappa角(°)	角膜Q值	角膜球差(D)	角膜高阶像差(D)
MS－39	156	－0.04(－0.42，－0.41)	－0.16(－0.46，－0.53)	0.23( 0.02，－0.56)	0.43(－0.37，－1.16)
Pentacam	156	0.18( 0.00，－0.42)	－0.29(－1.03，－0.01)	0.15(－0.13，－0.34)	0.37( 0.23，－1.90)
Z值		－10.28^b	－9.75^a	－9.50^a	－6.76^a
P值		<0.05	<0.05	<0.05	<0.05

检查设备	眼数	平坦轴角膜曲率K1 (D)	陡峭轴角膜曲率K2 (D)	角膜体积(mm³)	前房深度(mm)
MS－39	156	43.03(40.49，－46.44)	44.37(41.37，－48.89)	56.20(50.6，－63.8)	3.77(3.22，－4.50)
Pentacam	156	42.08(40.10，－42.05)	44.30(41.20，－48.70)	59.70(54.2，－67.6)	3.71(3.15，－4.45)
Z值		－8.56^a	－4.50^a	－10.87^b	－7.56^a
P值		<0.05	<0.05	<0.05	<0.05
检查设备	眼数	Kappa角(°)	角膜Q值	角膜球差(D)	角膜高阶像差(D)
MS－39	156	－0.04(－0.42，－0.41)	－0.16(－0.46，－0.53)	0.23( 0.02，－0.56)	0.43(－0.37，－1.16)
Pentacam	156	0.18( 0.00，－0.42)	－0.29(－1.03，－0.01)	0.15(－0.13，－0.34)	0.37( 0.23，－1.90)
Z值		－10.28^b	－9.75^a	－9.50^a	－6.76^a
P值		<0.05	<0.05	<0.05	<0.05

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