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Chinese Journal of Ophthalmologic Medicine(Electronic Edition) ›› 2022, Vol. 12 ›› Issue (05): 257-261. doi: 10.3877/cma.j.issn.2095-2007.2022.05.001

• Editorial • Previous Articles     Next Articles

Pay attention to the construction strategies of ophthalmic microneedle system

Chenxin Geng1, Haozhe Yu2, Yun Feng2,()   

  1. 1. Bachelor′s degree in 2018, Peking University School of Stomatology, Peking University Health Science Center, Beijing 100191, China
    2. Department of Ophthalmology, Peking University Third Hospital, Institute of Medical Technology, Peking University Health Science Center, Beijing 100191, China
  • Received:2022-02-01 Online:2022-10-28 Published:2023-02-02
  • Contact: Yun Feng

Abstract:

Ophthalmic microneedles is a novel system drug formulations for eyes, and consists of micron-scale needle arrays. Compared with traditional approaches such as topical and intravitreal routes, microneedles achieve more painless and efficient drug delivery, owing to its ability to overcome the barrier function of ocular tissues. Recently, the research about microneedles constructing new ways of drug delivery has been making progress. However, at present domestic researcher paid little attention to it. The recent progress onthe advantages of microneedles, the system construction strategy, security and existing problems were reviewed in this paper.

Key words: Ocular drug delivery, Microneedles, Minimally-invasive technique, Coated microneedles

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