The mechanism and treatment of high intraocular pressure and glaucoma caused by thyroid-associated ophthalmopathy

doi:10.3877/cma.j.issn.2095-2007.2020.06.011

Abstract

Abstract:

The occurrence of thyroid-associated ophthalmopathy (TAO), known as Grave′s ophthalmopathy, often accompanied orbital lesions. It is often as the major clinical manifestation that eyelid retraction, eyeball protrusion, double vision, extraocular muscle edema, and fibrosis. Due to various factors such as ocular muscle degeneration, increased orbital pressure, and the use of hormonal drugs, a considerable number of patients with TAO have elevated ocular hypertension (OHT) and glaucoma. Unlike primary glaucoma, secondary OHT and open angle glaucoma caused by TAO can be controlled after removing TAO. The drug therapy, radiation therapy, and surgical procedure were major treatment methods. The mechanism and treatment of high intraocular pressure and glaucoma caused by TAO was reviewed, which to provide data for better clinical diagnosis and treatment of secondary OHT and glaucoma.

Key words: Thyroid-associated ophthalmopathy, Thyroid stimulating hormone receptor, Secondary high intraocular pressure, Secondary glaucoma, Orbital decompression

Mingshen Ma, Yi Fan, Yueyue Li, Fan Su, Xinji Yang. The mechanism and treatment of high intraocular pressure and glaucoma caused by thyroid-associated ophthalmopathy[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2020, 10(06): 380-384.

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