The advances on immunological links between allergic inflammation and myopia development

doi:10.3877/cma.j.issn.2095-2007.2026.01.008

Abstract

Abstract:

The onset and progression of myopia to be predominantly was regulated by environmental and genetic factors. However, in recent years, accumulating clinical and basic research evidence has suggested that immune-mediated and allergic inflammation may play a non-negligible regulatory role in axial elongation during myopia development. The comorbidity between two highly prevalent diseases that affect nearly half of the global population. Paying attention the associations between allergic diseases and myopia was meaningful. The current research progress on the relationship between allergic immune imbalance, ocular allergic diseases, the immune composition of the eye, immune inflammation and myopia were systematically reviewed and analyzed, with the aim of providing potential insights for both clinical and basic research on myopia prevention and treatment from the perspectives of immune regulation and targeted intervention.

Key words: Immune inflammation, Allergy, Mast cells, Myopia

Wenying Guan, Zuguo Liu. The advances on immunological links between allergic inflammation and myopia development[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2026, 16(01): 43-47.

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