Research progress in the characteristics of vitreoretinal interface and its related diseases

doi:10.3877/cma.j.issn.2095-2007.2025.02.009

Abstract

Abstract:

Swept-source optical coherence tomography（SS-OCT），with its rapid scanning speed and high resolution，has significantly enhanced both the breadth and depth of vitreoretinal interface（VRI）imaging，substantially advancing our understanding，diagnosis，and treatment of VRI-related disorders.SSOCT enables comprehensive imaging and assessment of the posterior precortical vitreous pocket（PPVP），posterior vitreous detachment（PVD），and vitreous cortex remnant（VCR）that remain adherent to the retinal surface due to incomplete PVD.The PPVP，serving as an early indicator of vitreous liquefaction，exhibits morphological changes that are intimately associated with the dynamic progression of PVD.Different stages or states of PVD significantly influence the development，treatment，and prognosis of macular diseases，including age-related macular degeneration（AMD），macular edema，macular hole，epiretinal membrane，and high myopia.Notably，VCR represent a crucial factor affecting the therapeutic outcomes of rhegmatogenous retinal detachment（rRD）.The recent advances in VRI-related diseases through an analysis of anatomical characteristics and pathological mechanisms were reviewed comprehensively.

Key words: Vitreoretinal interface, Posterior vitreous detachment, Posterior precortical vitreous pockets, Vitreous cortex remnants, Swept-source optical coherence tomography

Xinyue Lan, Zhengwei Zhang. Research progress in the characteristics of vitreoretinal interface and its related diseases[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2025, 15(02): 114-118.

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References 49

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