Abstract:

Normal corneal endothelial function is one of the basic conditions to maintain corneal transparency.Corneal endothelium is a monolayer of hexagonal cells，which plays a key role in regulating corneal hydration and transparency.All kinds of internal eye surgery may cause varying degrees of damage to corneal endothelial cells，leading to postoperative corneal edema，even corneal endothelial decompensation，which seriously affects vision.In recent years，with the extensive development of internal eye surgery，the incidence of corneal endothelial decompensation has increased year by year.Identifying whether corneal edema after internal eye surgery is irreversible corneal endothelial decompensation is of great significance to decide whether to use drug conservative treatment to promote the regression of corneal edema or to carry out corneal endothelial keratoplasty in time to improve the prognosis of visual acuity.For the patients with postoperative corneal edema，early surgery is worried about over treatment；late operation missed the opportunity of corneal endothelial keratoplasty.Therefore，the“early”and“late”of corneal endothelial keratoplasty for corneal edema after internal eye surgery is a topic worthy of wide attention and discussion.The pros and cons and the basis were reviewed.

Key words: Corneal edema, Corneal endothelial decompensation, Corneal endothelial keratoplasty, Cornea