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Chinese Journal of Ophthalmologic Medicine(Electronic Edition) ›› 2022, Vol. 12 ›› Issue (06): 372-376. doi: 10.3877/cma.j.issn.2095-2007.2022.06.010

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Research progress on the relationship between changes of ocular surface flora and dry eye

Dalan Jing1, Xiaodan Jiang2, Jiarui Yang2, Xuemin Li2,()   

  1. 1. Doctoral degree 2020, Peking University Third Hospital, Peking University Eye Center, Beijing 100191, China
    2. Peking University Third Hospital, Peking University Eye Center, Peking University Third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing 100191, China
  • Received:2021-08-04 Online:2022-12-28 Published:2023-03-02
  • Contact: Xuemin Li

Abstract:

Dry eye is a multifactorial ocular surface disease. Currently, its incidence rate is rising rapidly, and has become an increasingly serious public health problem. The relevant literatures has shown that the state of dry eye patients′ ocular surface flora is related to the severity of the disease. Therefore, to investigate the pathogenesis of dry eye, from the perspective of ocular surface flora has been a hot research topic. In this paper, the relationship between changes of ocular surface flora and dry eye sign from the perspective of bacterium isolated from ocular surface of patients with dry eye was reviewed, in order to provide a basis for the management of dry eye risk factors and clinical treatment.

Key words: Ocular surface, Dry eye disease, Isolated bacterium, Mechanism, Risk factors, Treatment

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