Epidemiological analysis on diopter and related factors before and after cycloplegia in adults

doi:10.3877/cma.j.issn.2095-2007.2020.03.007

Abstract

Abstract:

Objective

The aim of this study was to explore the changes of diopter measurement before and after cycloplegia in adults and analysis of its related factors.

Methods

710 rural people (1410 eyes) in Yongnian County of Handan, Northern China were selected to participate in the measurement of diopter and ocular biological parameters. Among of them, there were 364 male (721 eyes) and 346 female (689 eyes). Automatic computer refractometer was used for diopter between after and before cycloplegia. Ocular biological parameters were taken by Ophthalmic A-scan before cycloplegia. Paired t-test was used for SE before and after cycloplegia. The consistency of SE before and after cycloplegia was evaluated by Bland-Altman plots among different age groups. The comparison between corneal curvature (K), len thickness (LT), anerior chamber depth (ACD), axis length (AL), nuclear opacity (NO), nuclear color (NC), cortical (C), posterior subcapsular cataract (PSC) and SE after cycloplegia in different genders was analyzed by linear mixed model. Pearson correlation analysis was used for ocular biological parameters.

Results

The mean SE of 710 cases (1410 eyes) before and after cycloplegia was respectively (-0.37±1.22) D and (0.13±1.11) D with statistical significance (t=-25.75, P<0.05). Bland-Altman analysis showed that the hyperopia drift of SE after cycloplegia decreased with the increasing of age. The characteristics of LT, NO, NC, C were positively correlated with SE after cycloplegia. After Person correlation analysis, there was significant difference among them (r=0.13, 0.11, 0.11, 0.07; P<0.05). There was a negative correlation between K, ACD, AL, PSC and SE. After Person correlation analysis, there was significant difference among them (r=-0.12, -0.17, -0.20, -0.13; P<0.05). Myopia was negatively correlated with Al, NO, NC, C and PSC. After Person correlation analysis, there was significant difference among them (r=-0.22, -0.15, -0.15, -0.14, -0.42; P<0.05).

Conclusions

The hyperopia shift of SE occurred after cycloplegia, which disappeared with the increasing of age. K, ACD, LT, AL, NO, NC, C and PSC were all related to SE after cycloplegia, among which AL, NO, NC, C and PSC were the influencing factors for myopia.

Key words: Diopter, Central corneal thickness, Ocular axis, Anterior chamber depth, Lens opacity classification system, Adult

Dayong Bai, Li Li, Shifei Wei, Sizhen Li, Ye Zhang, Jie Hao, Ningli Wang. Epidemiological analysis on diopter and related factors before and after cycloplegia in adults[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2020, 10(03): 166-171.

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性别	眼数(只)	等效球镜(D)	角膜曲率K值(D)	中央角膜厚度(μm)	前房深度(mm)	晶状体厚度(mm)
男	721	0.15±1.19	43.65±1.45	540.65±27.51	2.94±0.34	4.54±0.42
女	689	0.10±1.03	44.41±1.47	540.10±28.67	2.81±0.36	4.50±0.40
t值		-0.58	7.08	-0.22	-5.61	-1.65
P值		>0.05	<0.05	>0.05	<0.05	>0.05
性别	眼数(只)	眼轴长度(mm)	晶状体混浊度	晶状体颜色	皮质性白内障	后囊下性白内障
男	721	23.26±0.81	2.78±0.45	2.78±0.45	0.23±0.54	0.14±0.29
女	689	22.87±1.04	2.66±0.39	2.66±0.39	0.29±0.72	0.12±0.22
t值		-6.69	-3.87	-3.87	1.31	-0.99
P值		<0.05	<0.05	<0.05	>0.05	>0.05

性别	眼数(只)	等效球镜(D)	角膜曲率K值(D)	中央角膜厚度(μm)	前房深度(mm)	晶状体厚度(mm)
男	721	0.15±1.19	43.65±1.45	540.65±27.51	2.94±0.34	4.54±0.42
女	689	0.10±1.03	44.41±1.47	540.10±28.67	2.81±0.36	4.50±0.40
t值		-0.58	7.08	-0.22	-5.61	-1.65
P值		>0.05	<0.05	>0.05	<0.05	>0.05
性别	眼数(只)	眼轴长度(mm)	晶状体混浊度	晶状体颜色	皮质性白内障	后囊下性白内障
男	721	23.26±0.81	2.78±0.45	2.78±0.45	0.23±0.54	0.14±0.29
女	689	22.87±1.04	2.66±0.39	2.66±0.39	0.29±0.72	0.12±0.22
t值		-6.69	-3.87	-3.87	1.31	-0.99
P值		<0.05	<0.05	<0.05	>0.05	>0.05

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