Pay attention to the mechanism of intraocular pressure lowering in Schlemm related surgery for primary open angle glaucoma

doi:10.3877/cma.j.issn.2095-2007.2017.05.001

Abstract

Abstract:

The treatment of glaucoma mainly includes drug therapy, laser treatment and surgical treatment, three of which mainly include peripheral iridectomy and filtering surgery. Primary open-angle glaucoma (POAG) aqueous outflow blocked by irradiating-Schlemm system, therefore, the trabecular meshwork of-Schlemm tube system treatment is the key to the treatment of POAG. In the treatment of POAG, filtering surgery has always played an important role. Filtration surgery, and Schlemm related operation is mainly divided into two categories, one is to guide and help the real water flow into the Schlemm tube or reduce the resistance of water flow into the real operation, such as trabeculectomy, trabecular ablation, Glaukos iStent micro stent implantation and selective laser trabeculoplasty; on the other one is the restoration and reconstruction of Schlemm canal operation, such as Schlemm tube and Schlemm tube dilatation angioplasty etc. In this paper, the principle, method, effect and latest research progress of the above operations are reviewed.

Key words: Primary open-angle glaucoma, Filtering surgery, Schlemm′s cannal

Hong Zhang, Junming Wang. Pay attention to the mechanism of intraocular pressure lowering in Schlemm related surgery for primary open angle glaucoma[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2017, 07(05): 193-197.

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References 56

[1]	Johnson MC, Kamm RD. The role of Schlemm's canal in aqueous outflow from the human eye[J]. Invest Ophthalmol Vis Sci, 1983, 24(3):320-325.
[2]	Teekhasaenee C, Ritch R. Combined phacoemulsification and goniosynechialysis for uncontrolled chronic angle－closure glaucoma after acute angle－closure glaucoma[J]. Ophthalmology, 1999, 106(4):669-675.
[3]	Cronemberger S, Loredo AF, Faria DSD, et al. Efficacy of goniosynechialysis in the treatment of chronic angle－closure glaucoma: a five－case report Eficácia da goniossinequiálise no tratamento do glaucoma crônico de ângulo fechado: relato de cinco casos[J]. Revista Brasileira De Oftalmologia, 2013, 72(1):50-53.
[4]	Kiuchi Y, Tsujino C, Nakamura T, et al. Phacoemulsification and trabeculotomy combined with goniosynechialysis for uncontrollable chronic angle－closure glaucoma[J]. Ophthalmic Surgery Lasers Imaging, 2010, 41(3):348-354.
[5]	Sawada A, Sakuma T, Yamamoto T, et al. Appositional angle closure in eyes with narrow angles: comparison between the fellow eyes of acute angle－closure glaucoma and normotensive cases[J]. Journal of Glaucoma, 1997, 6(5):288-292.
[6]	Sng CCA, Aquino MCD, Liao J, et al. Pretreatment Anterior Segment Imaging During Acute Primary Angle Closure : Insights into Angle Closure Mechanisms in the Acute Phase[J]. Ophthalmology, 2014, 121(1):119-125.
[7]	Lowe RF. Aetiology of the anatomical basis for primary angle－closure glaucoma. Biometrical comparisons between normal eyes and eyes with primary angle－closure glaucoma[J]. Bri J Ophthalmol, 1970, 54(3):161-169.
[8]	Yuen NS, Chan OC, Hui SP, et al. Combined phacoemulsification and nonpenetrating deep sclerectomy in the treatment of chronic angle－closure glaucoma with cataract[J]. European Journal of Ophthalmology, 2007, 17(17):208-215.
[9]	Razeghinejad MR, Rahat F. Combined phacoemulsification and viscogoniosynechialysis in the management of patients with chronic angle closure glaucoma[J]. International Ophthalmology, 2010, 30(4):353-359.
[10]	Hong J, Yang Y, Wei A, et al. Schlemm's canal expands after trabeculectomy in patients with primary angle－closure glaucoma[J]. Invest Ophthalmol Vis Sci, 2014, 55(9):5637-5642.
[11]	Mansouri K, Shaarawy T. Update on Schlemm's Canal Based Procedures[J]. Middle East African Journal of Ophthalmology, 1900, 22(1):38-44.
[12]	Yan X, Li M, Chen Z, et al. Schlemm's Canal and Trabecular Meshwork in Eyes with Primary Open Angle Glaucoma: A Comparative Study Using High－Frequency Ultrasound Biomicroscopy[J]. Plos One, 2016, 11(1):e0145824.
[13]	Yan X, Li M, Song Y, et al. Influence of Exercise on Intraocular Pressure, Schlemm's Canal, and the Trabecular Meshwork[J]. Invest Ophthalmol Vis Sci, 2016, 57(11):4733-4739.
[14]	Li M, Zhao Y, Yan X, et al. The Relationship between the 24－hour Fluctuations in Schlemm's Canal and Intraocular Pressure: An Observational Study using High－Frequency Ultrasound Biomicroscopy[J]. Current Eye Research, 2017,37(11):1-7.
[15]	Ethier CR, Coloma FM, Sit AJ, et al. Two pore types in the inner－wall endothelium of Schlemm's canal[J]. Invest Ophthalmol Vis Sci, 1998, 39(11):2041-2048.
[16]	Ten Hulzen RD, Johnson DH. Effect of fixation pressure on juxtacanalicular tissue and Schlemm's canal[J]. Invest Ophthalmol Vis Sci, 1996, 37(1):114-124.
[17]	Bill A, Svedbergh B. Scanning electron microscopic studies of the trabecular meshwork and the canal of Schlemm－an attempt to localize the main resistance to outflow of aqueous humor in man[J]. Acta Ophthalmol, 1972, 50(3):295-320.
[18]	Allingham RR, Kater AW, Ethier CR. Schlemm's canal and primary open angle glaucoma: Correlation between Schlemm's canal dimensions and outflow facility[J]. Experimental Eye Research, 1996, 62(1):101-109.
[19]	Johnson M, Chan D, Read AT, et al. The pore density in the inner wall endothelium of Schlemm's canal of glaucomatous eyes[J]. Invest Ophthalmol Vis Sci, 2002, 43(9):2950-2955.
[20]	Overby DR, Zhou EH, Vargas－Pinto R, et al. Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma[J]. Proceedings of the National Academy of Sciences of the United States of America, 2014, 111(38):13876-13881.
[21]	Zhou EH, Krishnan R, Stamer WD, et al. Mechanical responsiveness of the endothelial cell of Schlemm's canal: scope, variability and its potential role in controlling aqueous humour outflow[J]. Journal of the Royal Society Interface, 2012, 9(71):1144-1155.
[22]	Last JA, Pan T, Ding Y, et al. Elastic Modulus Determination of Normal and Glaucomatous Human Trabecular Meshwork[J]. Invest Ophthalmol Vis Sci, 2011, 52(5):2147-2152.
[23]	Morgan JT, Raghunathan VK, Chang YR, et al. The intrinsic stiffness of human trabecular meshwork cells increases with senescence[J]. Oncotarget, 2015, 6(17):15362-15374.
[24]	Ainsworth JR, Lee WR. Effects of age and rapid high－pressure fixation on the morphology of Schlemm's canal[J]. Invest Ophthalmol Vis Sci, 1990, 31(4):745-750.
[25]	Grierson I, Howes RC, Wang Q. Age－related changes in the canal of Schlemm[J]. Experimental Eye Research, 1984, 39(4):505-512.
[26]	Swain DL, Ho J, Lai J, et al. Shorter scleral spur in eyes with primary open－angle glaucoma[J]. Invest Ophthalmol Vis Sci, 2015, 56(3):1638-1648.
[27]	Hann CR, Fautsch MP. Preferential Fluid Flow in the Human Trabecular Meshwork Near Collector Channels[J]. Invest Ophthalmol Vis Sci, 2009, 50(4):1692-1697.
[28]	Allingham RR, Kater AW, Ethier CR, et al. The relationship between pore density and outflow facility in human eyes[J]. Invest Ophthalmol Vis Sci, 1992, 33(5):1661-1667.
[29]	Battista SA, Lu Z, Hofmann S, et al. Reduction of the available area for aqueous humor outflow and increase in meshwork herniations into collector channels following acute IOP elevation in bovine eyes[J]. Invest Ophthalmol Vis Sci, 2008, 49(12):5346-5352.
[30]	Lu Z, Overby DR, Scott PA, et al. The mechanism of increasing outflow facility by rho－kinase inhibition with Y－27632 in bovine eyes[J]. Experimental Eye Research, 2008, 86(2):271-281.
[31]	Cha EDK, Jia X, Gong L, et al. Variations in Active Outflow Along the Trabecular Outflow Pathway[J]. Experimental Eye Research, 2016, 146(5):354-360.
[32]	Van Buskirk EM. Anatomic correlates of changing aqueous outflow facility in excised human eyes[J]. Invest Ophthalmol Vis Sci, 1982, 22(5):625-632.
[33]	Robert AMMD. Circumferential Flow in Schlemm's Canal[J]. American Journal of Ophthalmology, 1979, 88(3):585-591.
[34]	Moses RA, GW Jr, Etheridge EL, et al. Schlemm's canal: the effect of intraocular pressure[J]. Invest Ophthalmol Vis Sci, 1981, 20(1):61-68.
[35]	Li G, Farsiu S, Chiu SJ, et al. Pilocarpine－Induced Dilation of Schlemm's Canal and Prevention of Lumen Collapse at Elevated Intraocular Pressures in Living Mice Visualized by OCT[J]. Invest Ophthalmol Vis Sci, 2014, 55(6):3737-3746.
[36]	Johnstone MA, Grant WM. Microsurgery of Schlemm's canal and the human aqueous outflow system[J]. Am J Ophthalmol, 1973, 76(6):906-917.
[37]	Tam LCS, Reinatorres E, Sherwood JM, et al. Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight－Junctions of Schlemm′s Canal Endothelia[J]. Scientific Reports, 2017, 7(1):40717-40730.
[38]	Gong H, Francis A. Schlemm′s Canal and Collector Channels as Therapeutic Targets[M]. New York: Springer, 2014: 3-25.
[39]	Gong H, Qi H, Sun W, et al. Design and synthesis of a series of pyrido[2，3－d]pyrimidine derivatives as CCR4 antagonists[J]. Molecules, 2012, 17(8):9961-9970.
[40]	Zhu JY, Ye W, Wang T, et al. Reversible changes in aqueous outflow facility, hydrodynamics, and morphology following acute intraocular pressure variation in bovine eyes[J]. Chinese Medical Journal, 2013, 126(8):1451-1457.
[41]	Caprioli J, Coleman AL. Intraocular pressure fluctuation a risk factor for visual field progression at low intraocular pressures in the advanced glaucoma intervention study[J]. Ophthalmology, 2008, 115(7):1123-1129.
[42]	Lewis RA, Von WK, Tetz M, et al. Canaloplasty: circumferential viscodilation and tensioning of Schlemm′s canal using a flexible microcatheter for the treatment of open－angle glaucoma in adults: interim clinical study analysis[J]. J Cataract Refract Surg, 2007, 33(7):1217-1226.
[43]	Shingleton B, Tetz M, Korber N. Circumferential viscodilation and tensioning of Schlemm canal(canaloplasty) with temporal clear corneal phacoemulsification cataract surgery for open－angle glaucoma and visually significant cataract : One－year results[J]. J Cataract Refract Surg, 2008, 34(3):433-440.
[44]	Wamsley S, Moster MR, Rai S, et al. Results of the use of the Ex－PRESS miniature glaucoma implant in technically challenging, advanced glaucoma cases: a clinical pilot study[J]. Am J Ophthalmol, 2005, 138(6):1049-1051.
[45]	Good TJ, Kahook MY. Assessment of bleb morphologic features and postoperative outcomes after Ex－PRESS drainage device implantation versus trabeculectomy[J]. Am J Ophthalmol, 2011, 151(3):507-513.
[46]	Zhu J, Zhao W, Shao J, et al. Long－term efficacy comparison between goniosynechialysis and combination of phacoemulsification with goniosynechialysis for the management of chronic angle closure glaucoma[J]. Chinese Journal of Experimental Ophthalmology, 2013, 31(10):964-967.
[47]	Wang H, Tang X, Sun X, et al. Phacoemulsification combined with endoscopically controlled goniosynechialysis for angle－closure glaucoma co－existing cataract: a report of preliminary efficacy[J]. Ophthalmology in China, 2014, 23(1):18-21.
[48]	Gottanka J, Johnson DH, Martus P, et al. Severity of optic nerve damage in eyes with POAG is correlated with changes in the trabecular meshwork[J]. Journal of Glaucoma, 1997, 124(2):123-132.
[49]	Akil H, Chopra V, Huang A, et al. Clinical results of ab interno trabeculotomy using the Trabectome in patients with pigmentary glaucoma compared to primary open angle glaucoma[J]. Clinical & Experimental Ophthalmology, 2016, 44(7):563-569.
[50]	Minckler DS, Baerveldt G, Alfaro MR, et al. Clinical results with the Trabectome for treatment of open－angle glaucoma[J]. Ophthalmology, 2005, 112(6):962-967.
[51]	Gonnermann J, Bertelmann E, Pahlitzsch M, et al. Contralateral eye comparison study in MICS & MIGS: Trabectome^®vs. iStent inject^®[J]. Graefes Archive for Clinical & Experimental Ophthalmology, 2017, 255(2):1-7.
[52]	Nichamin LD. Glaukos iStent Trabecular Micro－Bypass[J]. Middle East African Journal of Ophthalmology, 2009, 16(3):138-140.
[53]	Schlote T, Kynigopoulos M. Selective laser trabeculoplasty (SLT): 1－year results in early and advanced open angle glaucoma[J]. International Ophthalmology, 2016, 36(1):55-61.
[54]	Damji KF, Bovell AM, Hodge WG, et al. Selective laser trabeculoplasty versus argon laser trabeculoplasty: results from a 1－year randomised clinical trial[J]. Bri J Ophthalmol, 2006, 90(12):1490-1494.
[55]	Serra R, Johnson M, Filvaroff EH, et al. Expression of a truncated, kinase－defective TGF－beta type Ⅱ receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis[J]. Journal of Cell Biology, 1997, 139(2):541-552.
[56]	王宁利，王怀洲，洪洁，等. 房水流出通路重建术与Schlemm管成形术治疗开角型青光眼的初步临床对比研究[J]. 中华眼科杂志，2014(5):338-342.

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