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中华眼科医学杂志(电子版) ›› 2019, Vol. 09 ›› Issue (04) : 199 -205. doi: 10.3877/cma.j.issn.2095-2007.2019.04.002

所属专题: 指南共识

论著

我国原发性青光眼诊断和治疗专家共识遵循情况的调查
乔春艳1, 张慧1, 曹凯2, 王辉3, 赵爱萍4, 王怀洲1, 唐炘1, 石砚1, 张纯5, 王宁利6,()   
  1. 1. 100730 首都医科大学附属北京同仁医院 北京眼科中心 北京市眼科学与视觉科学重点实验室
    2. 100005 北京市眼科研究所
    4. 100024 北京科林利康医学研究有限公司
    5. 100083 北京大学附属第三医院眼科 青光眼百家联盟课题组
    6. 100730 首都医科大学附属北京同仁医院 北京眼科中心 北京市眼科学与视觉科学重点实验室;100005 北京市眼科研究所
  • 收稿日期:2019-07-26 出版日期:2019-08-28
  • 通信作者: 王宁利
  • 基金资助:
    国家自然科学基金项目(81570837)

A survey on the compliance ofthe expert consensus in the diagnosis and treatment of primary glaucoma in China

Chunyan Qiao1, Hui Zhang1, Kai Cao2, Hui Wang3, Aiping Zhao4, Huaizhou Wang1, Xin Tang1, Yan Shi1, Chun Zhang5, Ningli Wang6,()   

  1. 1. Beijing Tongren Eye Center, BeijingTongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab., Beijing 100730, China
    2. Beijing Institute of Ophthalmology, Beijing 100005, China
    3. Beijing Tongren Eye Center, BeijingTongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab., Beijing 100730, China; Beijing Institute of Ophthalmology, Beijing 100005, China
    4. Beijing Clinical Service Center, Beijing 100024, China
    5. Chinese Glaucoma Study Consortium, Peking University Third Hospital, Beijing 100083, China
  • Received:2019-07-26 Published:2019-08-28
  • Corresponding author: Ningli Wang
引用本文:

乔春艳, 张慧, 曹凯, 王辉, 赵爱萍, 王怀洲, 唐炘, 石砚, 张纯, 王宁利. 我国原发性青光眼诊断和治疗专家共识遵循情况的调查[J]. 中华眼科医学杂志(电子版), 2019, 09(04): 199-205.

Chunyan Qiao, Hui Zhang, Kai Cao, Hui Wang, Aiping Zhao, Huaizhou Wang, Xin Tang, Yan Shi, Chun Zhang, Ningli Wang. A survey on the compliance ofthe expert consensus in the diagnosis and treatment of primary glaucoma in China[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2019, 09(04): 199-205.

目的

了解眼科医师遵循我国原发性青光眼诊断和治疗专家共识的现状,评估在面授指导和网络教育后对其知晓度及依从性的效果。

方法

采用横断面非随机抽样调查法,收集2018年10月至2019年8月填答我国原发性青光眼诊断和治疗专家共识问卷调查的临床眼科从业医师的数据,通过面授指导、网络直播和视频回放的方式进行专家共识的系列培训,培训前后通过微信两次发送问卷调查,比较参加培训和未参加培训医师对其知晓度和依从率的差异。采用卡方检验对计数资料进行组间比较,采用秩和检验对等级资料进行组间比较。采用因子分析对问卷的结构效度进行分析;采用最大方差法对因子进行旋转;采用Kaiser-Meyer-Olkin和Bartlett检验对数据结构进行检验。

结果

第一次调查收到715份问卷,第二次调查收到515份问卷。正高级职称的医师和青光眼专科医师培训参与率更高( χ2=11.54,59.114;P<0.05)。第一次调查共识依从率为7.55%~85.59%,在51.75%~85.59%之间居多。正常性青光眼、高眼压症的排他性诊断、原发性闭角型青光眼激发试验阴性的意义等基本概念知晓率较高(83.36%~85.59%)。依从率最低的是Goldman压平眼压计的使用(7.55%),其次是采用改良的PACG激发试验(14.45%~28.20%),对青光眼性视神经损害的ISNT原则正确理解率也较低(40.42%)。培训后再次问卷调查,未接受培训者总体依从率在17.38%~82.62%,接受培训者总体依从率在20.47%~96.34%。其中,房角镜宽窄分级的判断、青光眼性视神经损害和盘沿下方>上方>鼻侧>颞侧原则(ISNT原则)的理解、视野的判读、以及原发性闭角型青光眼的分类方法、正常眼压性青光眼的定义及高眼压症治疗时机等,接受培训者的知晓度较未接受培训的均提高至11%~26%,且有统计学意义(χ2=5.687~31.568, P<0.05)。

结论

目前我国原发性青光眼诊断和治疗专家共识的知晓度及依从率有待提高,通过面授指导联合网络培训的方式,可有效提高知晓度和依从率。若通过强制性培训、建立青光眼专家与非青光眼专家的团队协作等方式,将有助于推动专家共识和指南在临床工作中的实施。

Objective

This study was aim to obtain the current situation of ophthalmologists following the expert consensus in the diagnosis and treatment of primary glaucoma in China, and evaluate the effect of improving the compliance of expert consensus by live lectures and webcast training.

Methods

Cross-section non-random sampling network WeChat questionnaires were used in the survey. From October 2018 to August 2019, questionnaires designed according to the expert consensus of the diagnosis and treatment of primary glaucoma in China were collected from ophthalmologists. The glaucoma expert consensus training was carried out through live lectures, live broadcast and video playback. Two questionnaires were sent through WeChat before and after the training. The differences of consensus awareness and compliance rate were compared the groups who participated in the training or not. Chi-square test was used to compare the counting data between groups, and rank sum test was used to compare the ranking data between groups. Factor analysis was used to analyze the structural validity of the questionnaire, and maximum variance method was used to rotate factors. Kaiser-Meyer-Olkin (KMO) and Bartlett tests.

Results

715 questionnaires were received during the first survey and 515 questionnaires were received during the second survey after the training. The training rate of doctors with senior titles and glaucoma specialists was higher than that of the other ophthalmologists ( χ2=11.541, 59.114; P<0.05). The consensus compliance rates during the first survey were 7.55% to 85.59%, and majority of them were 51.75% to 85.59%. The awareness rates of basic concepts such as normal tension glaucoma (NTG), exclusive diagnosis of ocular hypertension and negative significance of primary angle closure glaucoma (PACG) provocative test were higher (83.36% to 85.59%). The lowest compliance rate was the use of Goldmann tonometer (7.55%), followed by the modified PACG provocative test (14.45% to 28.20%). The correct understanding rate of inferior superior nasal temporal (ISNT) principle for glaucoma optic nerve damage was also low (40.42%). During the second survey after the training, the compliance rate was 17.38% to 82.62% in the group who did not attend the training, besides the overall compliance rate was 20.47% to 96.34% in the group who did. Among them, the compliance rate of those who received training was significantly higher than that of who did not, and the increase was between 11% and 26% with statistical difference in the judgment of the width and narrow grade of gonioscopy, the understanding of glaucoma optic nerve damage and ISNT principle, the interpretation of visual field, the classification of PACG, the definition of NTG, when to treat ocular hypertension, etc(χ2=5.687-31.568, P<0.05).

Conclusion

In current, the compliance of expert consensus on diagnosis and treatment of primary glaucoma in China needs to be improved. Live lectures and wechast training could effectively improve the cognition and compliance of expert consensus. It is necessary to promote the compliance of expert consensus and guidelines in clinical practice through mandatory training and teamwork between glaucoma experts and ophthalmologists.

表1 培训参与度与被调查者基本信息间的关系[人数(占比)]
表2 第二次问卷调查中能够正确理解条目的比较[人数(占比)]
调查项目 青光眼基本检查和诊断方法
测量眼压时需记录的目前使用降眼压药物情况 青光眼性视神经损害的表现 ISNT原则 分析视野结果时应注意一致性和可靠性 Humphrey视野可靠性指数 谢氏前房角分类法的具体内容 房角动静态检查操作的方法及意义
未参加培训的准确率 284(80.91%) 200(56.98%) 139(39.60%) 222(63.25%) 120(34.19%) 160(52.46%) 244(80.00%)
参加培训的准确率 142(86.59%) 135(82.32%) 88(53.66%) 116(70.73%) 74(45.12%) 159(75.71%) 197(93.81%)
χ2 2.523 31.568 8.964 2.773 5.687 28.519 19.277
P >0.05 <0.05 <0.05 >0.05 >0.05 <0.05 <0.05
调查项目 原发性开角型青光眼的诊断 原发性闭角型青光眼的诊断
分为高眼压型、正常眼压型、高眼压症三类 24 h眼压峰值应≤21 mmHg 高眼压症且CCT≤555 μm 全面筛查高危因素 开展激发试验 明暗室UBM的改良激发试验 3 min暗室评估房角的改良激发试验
未参加培训的准确率 286(81.48%) 169(61.68%) 236(67.24%) 188(61.64%) 147(48.20%) 53(17.38%) 63(20.66%)
参加培训的准确率 138(84.15%) 177(73.44%) 128(78.05%) 156(74.29%) 133(63.48%) 43(20.47%) 52(24.76%)
χ2 0.547 8.043 6.303 8.973 11.69 0.783 1.205
P >0.05 <0.05 <0.05 <0.05 <0.05 >0.05 >0.05
调查项目 原发性闭角型青光眼的诊断 原发性开角型青光眼的治疗原则 原发性闭角型青光眼的手术治疗原则
采用ISGEO分类、按房角关闭机制分类和临床症状学分类相结合的原则 设定个体化目标眼压 术式应考虑房角关闭范围、药物治疗效果、视盘和视野损害程度及眼压情况等
未参加培训的准确率 122(40.00%) 290(82.62%) 246(80.66%)
参加培训的准确率 125(59.52%) 158(96.34%) 191(90.95%)
χ2 18.987 18.59 10.247
P <0.05 <0.05 <0.05
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