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中华眼科医学杂志(电子版) ›› 2019, Vol. 09 ›› Issue (03) : 166 -171. doi: 10.3877/cma.j.issn.2095-2007.2019.03.007

病例报告

双眼Coats病合并单眼原始玻璃体持续增生症一例
代贺华1, 张芷萌1, 李如意1, 许静1, 王良海1, 李根林1,()   
  1. 1. 100730 首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科学与视觉科学重点实验室
  • 收稿日期:2019-01-07 出版日期:2019-06-28
  • 通信作者: 李根林
  • 基金资助:
    国家自然科学基金(81271046); 北京市自然科学基金项目暨北京市教育委员会科技发展计划重点项目(KZ201510025025)

Bilateral Coats′ disease combined with the unilateral persistent hyperplastic primary vitreous: a case report

Hehua Dai1, Zhimeng Zhang1, Ruyi Li1   

  • Received:2019-01-07 Published:2019-06-28
引用本文:

代贺华, 张芷萌, 李如意, 许静, 王良海, 李根林. 双眼Coats病合并单眼原始玻璃体持续增生症一例[J]. 中华眼科医学杂志(电子版), 2019, 09(03): 166-171.

Hehua Dai, Zhimeng Zhang, Ruyi Li. Bilateral Coats′ disease combined with the unilateral persistent hyperplastic primary vitreous: a case report[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2019, 09(03): 166-171.

图1 患者就诊时彩色眼底照相图 双眼视网膜血管扩张迂曲,大量黄白色渗出物,黄斑反光不见。图A显示右眼见自视乳头延伸至玻璃体的束状物;图B显示左眼视乳头边界模糊,充血水肿
图2 患者就诊时双眼彩色多普勒超声图像 A图示右眼;B图示左眼。双眼玻璃体内异常回声,与眼视盘回声相连,动度(+),后运动(-),玻璃体混浊,双眼局限性视网膜脱离。彩色多普勒血流成像上可见与视网膜中央动脉相延续的血流信号
图4 复查彩色数码眼底照相 图4A示右眼隐约可见视盘充血水肿,视网膜血管迂曲,伴有大量黄白色渗出;图4B示左眼底窥不清
图5 复查时双眼彩色多普勒超声检查图像 A图示右眼;B图示左眼。双眼玻璃体腔内异常回声,与视盘回声相连,动度(+),后运动(-),视网膜脱离。右眼玻璃体混浊,左眼视网膜下病变。彩色多普勒血流成像上可见与视网膜中央动脉相延续的血流信号
[1]
Sen M, Shields CL, Honavar SG,et al.Coats disease: An overview of classification, management and outcomes[J]. Indian J Ophthalmol. 2019 Jun;67(6):763-771.
[2]
Shields JA, Shields CL, Honavar SG, et al. Clinical variations and complications of Coats disease in 150 cases: the 2000 Sanford Gifford Memorial Lecture[J]. Am J Ophthalmol, 2001, 131(5): 561-571.
[3]
Morris B, Foot B, Mulvihill A. A population-based study of Coats disease in the United Kingdom Ⅰ:Epidemiology and clinicalfeatures at diagnosis[J]. Eye(Lond), 2010, 24(12): 1797-1801.
[4]
Sigler EJ, Randolph JC, Calzada JI, et al. Current management of Coats disease[J]. Surv Ophthalmol, 2014, 59(1): 30-46.
[5]
Grosso A, Pellegrini M, Cereda MG, et al. Pearls and pitfalls in diagnosis and management of coats disease[J]. Retina, 2015, 35(4): 614-623.
[6]
Zhang J, Jiang C, Ruan L, et al. Associations of cytokine concentrations in aqueous humour with retinal vascular abnormalities and exudation in Coats′ disease[J]. Acta Ophthalmol, 2019, 97(3): 319-324.
[7]
Saatci AO, Ayhan Z, Yaman A, et al. A 12-year-old girl with bilateral coats disease and ABCA4 gene mutation[J]. Case Rep Ophthalmol, 2018, 9(2): 375-380.
[8]
Peene G, Smets E, Legius E, et al. Unilateral Coats′-like disease and an intragenic deletion in the TERC gene: a case report[J]. Ophthalmic Genet, 2018, 39(2): 247-250.
[9]
Wu JH, Liu JH, Ko YC, et al. Haploinsufficiency of RCBTB1 is associated with Coats disease and familial exudative vitreoretinopathy[J]. Hum Mol Genet, 2016, 25(8): 1637-1647.
[10]
何璐,陈长征. 成人Coats病诊治进展[J]. 中华眼底病杂志2018, 34(3):299-303.
[11]
杨琼,魏文斌. Coats病的发病机制及治疗[J]. 国际眼科纵览2015, 39(1):39-43.
[12]
Yang X, Wang C, Su G. Recent advances in the diagnosis and treatment of Coats′ disease[J]. Int Ophthalmol, 2019, 39(4): 957-970.
[13]
Ong SS, Mruthyunjaya P, Stinnett S, et al. Macular features on spectral-domain optical coherence tomography imaging associated with visual acuity in Coats′ disease[J]. Invest Ophthalmol Vis Sci, 2018, 59(7): 3161-3174.
[14]
Muakkassa NW, de Carlo TE, Choudhry N, et al. Optical coherence tomography angiography findings in Coats′ disease[J]. Ophthalmic Surg Lasers Imaging Retina, 2016, 47(7): 632-635.
[15]
Warren CC, Young JB, Goldberg MR, et al. Findings in persistent retinopathy of prematurity[J]. Ophthalmic Surg Lasers Imaging Retina, 2018, 49(7): 497-503.
[16]
Li Y, Peng J, Li J, et al. The characteristics of digenic familial exudative vitreoretinopathy[J]. Graefes Arch Clin Exp Ophthalmol, 2018, 256(11): 2149-2156.
[17]
Kembhavi SA, Sable N, Vora T, et al. Leukokoria: All That′s White Is Not Retinoblastoma[J]. J Clin Oncol, 2011, 29(19): e586-587.
[18]
任湘,张明,陆方. 色素失禁症患者眼底及荧光素眼底血管造影影像特征观察[J]. 中华眼底病杂志2017, 33(5):534-535.
[19]
Cebeci Z, Bayraktar Ş,,Ylmaz YC, et al. Evaluation of follow-up and treatment results in Coats′ disease[J]. Turk J Ophthalmol, 2016, 46(5): 226-231.
[20]
Nucci P, Bandello F, Serafino M, et al. Selective photocoagulation in Coats disease: ten-year follow-up[J]. Eur J Ophthalmol, 12(6): 501-505.
[21]
Schefler AC, Berrocal AM, Murray TG. Advanced Coats′ disease. Management with repetitive aggressive laser ablation therapy[J]. Retina, 2008, 28(S3): S38-S41.
[22]
Reichstein DA, Recchia FM. Coats disease and exudative retinopathy[J]. Int Ophthalmol Clin, 2011, 51(1): 93-112.
[23]
Adam RS, Kertes PJ, Lam WC. Observations on the management of Coats′ disease: less is more[J]. Br J Ophthalmol, 2007, 91(3): 303-306.
[24]
Othman IS, Moussa M, Bouhaimed M. Management of lipid exudates in Coats disease by adjuvant intravitreal triamcinolone: effects and complications[J]. Br J Ophthalmol, 2010, 94(5): 606-610.
[25]
Kaul S, Uparkar M, Mody K, et al. Intravitreal anti-vascular endothelial growth factor agents as an adjunct in the management of Coats′ disease in children[J]. Indian J Ophthalmol, 2010, 58(1): 76-78.
[26]
Ramasubramanian A, Shields CL. Bevacizumab for Coats′ disease with exudative retinal detachment and risk of vitreoretinal traction[J]. Br J Ophthalmol, 2012, 96(3): 356-359.
[27]
Karacorlu M, Hocaoglu M, Sayman Muslubas I, et al. Long-term anatomical and functional outcomes following vitrectomy for advanced coats diseases[J]. Retina, 2017, 37(9): 1757-1764.
[28]
Kumari R, Saha BC. Bilateral persistent hyperplastic primary vitreous—a rare case report[J]. J Clin Diagn Res, 2017, 11(9): ND01.
[29]
Galhotra R, Gupta K, Kaur S, et al. Bilateral persistent hyperplastic primary vitreous: A rare entity[J]. Oman J Ophthalmol, 2012, 5(1): 58-60.
[30]
Chen C, Xiao H, Ding X. Persistent Fetal Vasculature[J]. Asia Pac J Ophthalmol (Phila), 2019, 8(1): 86-95.
[31]
Manschot WA. Persistent hyperplastic primary vitreous;special reference to preretinal glial tissue as a pathological characteristic and to the development of the primary vitreous[J]. AMA Arch Ophthalmol, 1958, 59(2): 188-203.
[32]
Shastry BS. Persistent hyperplastic primary vitreous: congenital malformation of the eye[J]. Clin Exp Ophthalmol, 2009, 37(9): 884-890.
[33]
Aponte EP, Pulido JS, Ellison JW, et al. A novel NDP mutation in an infant with unilateral persistent fetal vasculature and retinal vasculopathy[J]. Ophthalmic Genet, 2009, 30(2): 99-102.
[34]
Cerón O, Lou PL, Kroll AJ, et al. The vitreo-retinal manifestations of persistent hyperplasic primary vitreous (PHPV) and their management[J]. Int Ophthalmol Clin, 2008, 48(2): 53-62.
[35]
Zahavi A, Weinberger D, Snir M, et al. Management of severe persistent fetal vasculature: case series and review of the literature[J]. Int Ophthalmol, 2019, 39(3): 579-587.
[36]
Hu A, Yuan M, Liu F, et al. Ultrasonographic feature of persistent hyperplastic primary vitreous[J]. Eye Sci, 2014, 29(2): 100-103.
[37]
郑建美,林新霖,魏巍丽. 永存原始玻璃体增生症的临床特征及超声诊断价值[J]. 中外医疗2017, 36(26):188-189.
[38]
De la Huerta I, Mesi O, Murphy B, et al. Spectral domain optical coherence tomography imaging of the macula and vitreomacular interface in persistent fetal vasculature syndrome with posterior involvement[J]. Retina, 2019, 39(3): 581-586.
[39]
Cheung AY, Kashani AH, Drenser KA. Subretinal peri- papillary neovascularization associated with persistent fetal vasculature[J]. Retin Cases Brief Rep, 2014, 8(1): 83-86.
[40]
Jeng-Miller KW, Joseph A, Baumal CR. Fluorescein angiography in persistent fetal vasculature[J]. Ophthalmology, 2017, 124(4): 455.
[41]
Shen JH, Liu L, Wang NK, et al. Fluorescein angiography findings in unilateral persistent fetal vasculature[EB/OL]. (2018-11-28). http://dx.doi.org/10.1097/IAE.0000000000002398
[42]
张征宇,高爱英,鲜军舫,等. 眼球病变的影像学检查与诊断[J]. 中华放射学杂志2003, 37(2):181-183.
[43]
Bosjolie A, Ferrone P. Visual outcome in early vitrectomy for posterior persistent fetal vasculature associated with traction retinal detachment[J]. Retina, 2015, 35(3): 570-576.
[44]
Li L, Fan DB, Zhao YT, et al. Surgical treatment and visual outcomes of cataract with persistent hyperplastic primary vitreous[J]. Int J Ophthalmol, 2017, 10(3): 391-399.
[45]
Sudha D, Ganapathy A, Mohan P, et al. Clinical and genetic analysis of Indian patients with NDP-related retinopathies[J]. Int Ophthalmol, 2018, 38(3): 1251-1260.
[46]
张勤,张琦,赵培泉. NDP基因相关视网膜病变研究[J]. 临床儿科杂志2013, 31(5):481-483.
[47]
梅利斌,黄燕茹,潘乾,等. X连锁隐性遗传诺里病家系的NDP基因突变检测[J]. 中华眼科杂志2015, 51(5):360-363.
[48]
由冰,许可,孙腾洋,等. Norrie病及家族性渗出性玻璃体视网膜病变患者NDP基因突变分析及临床特征[J]. 中华实验眼科杂志2018, 36(7):539-543.
[49]
张天晓,赵秀丽,华芮,等. 我国诺里病家系NDP基因的突变分析[J]. 中华眼科杂志2012, 48(9):815-818.
[50]
杨琼,魏文斌,卢海,等. 22例中国Coats病患儿NDP基因检测分析[J]. 眼科2016(2):127-129.
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