切换至 "中华医学电子期刊资源库"

中华眼科医学杂志(电子版) ›› 2023, Vol. 13 ›› Issue (03) : 162 -166. doi: 10.3877/cma.j.issn.2095-2007.2023.03.007

综述

间歇性外斜视新型热点问题的研究进展
任美琪, 李俊红(), 冯张青   
  1. 030001 太原,山西医科大学第一临床医学院2020级硕士研究生
    030002 太原,山西省眼科医院斜视与小儿眼科
  • 收稿日期:2022-07-09 出版日期:2023-06-28
  • 通信作者: 李俊红
  • 基金资助:
    山西省卫生健康委科研课题项目(2020040); 山西省眼科医院院内科研基金项目(C201802)

Research progress on new hot issues of intermittent exotropia

Meiqi Ren, Junhong Li(), Zhangqing Feng   

  1. Master′s degree 2020, The First Clinical Medical College, Shanxi Medical University, Taiyuan 030001, China
    Strabismus and Pediatric Ophthalmology, Shanxi Eye Hospital, Taiyuan 030002, China
  • Received:2022-07-09 Published:2023-06-28
  • Corresponding author: Junhong Li
引用本文:

任美琪, 李俊红, 冯张青. 间歇性外斜视新型热点问题的研究进展[J]. 中华眼科医学杂志(电子版), 2023, 13(03): 162-166.

Meiqi Ren, Junhong Li, Zhangqing Feng. Research progress on new hot issues of intermittent exotropia[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2023, 13(03): 162-166.

间歇性外斜视(IXT)是斜视角度变化较大常伴不同程度立体视功能损害的临床常见眼病。目前,其诊断治疗过程中还存在诸多问题尚有争议。正确认识此病的发展与转归,采用高效的诊断流程并选择适宜的治疗方法对IXT患者维持视功能,改善其生活质量并减少复发具有临床价值。当前,IXT对患者立体视功能的损害与重建、与近视眼发生及发展的交互作用机制、观察随访治疗的综合运用以及借助人工智能的新型诊疗方法等已成为IXT研究的新型热点问题。本文中笔者就这些新型热点问题的研究进展进行综述,以期为临床诊断与治疗提供参考。

Intermittent exotropia (IXT) is a common clinical eye disease with large changes in strabismus angle and different degrees of stereopsis impairment. There are still many problems in its diagnosis and treatment. Correct understanding of the development and prognosis of the disease, selection of reasonable treatment methods, timely visual training, and improvement of diagnostic efficiency are all crucial to improving the quality of life and reducing recurrence for patients with IXT. The damage and reconstruction of stereoscopic function, the interaction with myopia, the integrated application of observation and follow-up treatment, and artificial intelligence diagnosis and treatment are new hot issues in the current IXT research. The research progress of these issuses were reviewed in this paper, aiming to provide the reference for diagnosis and treatment of IXT.

图1 Lactose十秒量表评分法具体步骤示意图
表1 人工智能在斜视领域的研究与应用项目
[1]
戴薇,付晶. 近视与间歇性外斜视交互影响的机制及关键临床科学问题[J]. 中国斜视与小儿眼科杂志202028(1):36-38.
[2]
Ekdawi NS, Nusz KJ, Diehl NN, et al. The development of myopia among children with intermittent exotropia[J]. Am J Ophthalmol, 2010, 149(3): 503-507.
[3]
Park Y, Ahn YJ, Park SH, et al. Interocular difference associated with myopic progression fllowing unilateral lateral rectus recession in early school-aged children[J].Jpn J Ophthalmol, 201963(6): 474-482.
[4]
Li X, Yang C, Zhang G, et al. Intermittent Exotropia Treatment with Dichoptic Visual Training Using a Unique Virtual Reality Platform[J]. Cyberpsychol Behav Soc Netw, 2019; 22(1): 22-30.
[5]
Fang C, Wu Y, Peng T, et al. Reading speed in school-age children with intermittent exotropia[J]. Sci Rep, 2022, 12(1): 9423.
[6]
Yildirim C, MutluFM, ChenY, et al. Assessment of central and peripheral fusion and near and distance stereoacuity in intermittent exotropic patients before and after strabismus surgery[J].Am J Ophthalmol, 1999, 128(2): 222-230.
[7]
洪洁,付晶,赵博文,等. 间歇性外斜视的斜视类型对立体视功能的影响[J]. 中国斜视与小儿眼科杂志201725(2):20-23.
[8]
扶城宾,何瑞霞,郭桂花,等. 双眼外直肌倾斜后徙术治疗集合不足型间歇性外斜视的疗效[J]. 国际眼科杂志202121(70):1249-1252.
[9]
Ren M, Wang Q, Wang L. Slanted bilateral lateral rectus recession for convergence insufficiency-type intermittent exotropia: a retrospective study[J]. BMC Ophthalmol, 2020, 20(1): 287.
[10]
Li Y, Lin H. Slanted recession on bilateral lateral rectus for the treatment of intermittent Exotropia with convergence insufficiency[J]. BMC Ophthalmol, 2022. 22(1): 134.
[11]
Farid MF, Abdelbaset EA. Surgical outcomes of three different surgical techniques for treatment of convergence insufficiency intermittent exotropia[J]. 2018, 32(4): 693-700.
[12]
Kim MK, Kim US, Cho MJ, et al. Hyperopic refractive errors as a prognostic factor in intermittent exotropia surgery[J]. Eye (Lond), 2015, 29(12): 1555-1560.
[13]
刘佩佩,付晶,董芳,等. 不同屈光状态的间歇性外斜视患者精细与粗糙立体视的究[J]. 中国斜视与小儿眼科杂志202028(3):18-21.
[14]
洪洁,付晶,赵博文,等. 间歇性外斜视患者的屈光状态对术后短期立体视功能重建的影响[J]. 眼科201726(3):169-173.
[15]
Wilson ME, Saunders RA, Trivedi RH. Pediatric ophthalmology: current thought and a practical guide[M]. Berlin: Springer-Verlag, 2009: 97-111.
[16]
Haggerty H, Richardson S, Hrisos S, et al. The Newcastle Control Score: a new method of grading the severity of intermittent distance exotropia[J]. Br J Ophthalmol, 2004, 88(2): 233-235.
[17]
Mohney BG, Holmes JM. An office-based scale for assessing control in intermittent exotropia[J]. Strabismus, 2006, 14(3): 147-150
[18]
Kim H, Kim DH, Ahn H, et al. Proposing a new scoring system in intermittent exotropia: towards a better assessment of control[J]. Can J Ophthalmol, 2017, 5(3): 235-239.
[19]
Moon Y, Kim H, Kim DH, et al. Lactose control scoring helps predict surgical outcomes for childhood intermittent exotropia[J]. Can J Ophthalmol, 2019, 54(6): 659-663.
[20]
Hatt SR, Leske DALicbermann L, et al. Quantifying variability in the measurement of control in intermittent exotro-pia[J]. J AAPOS. 2015, 19(1): 33-37.
[21]
Thuma TBT, Zhang QE, Sharpe J, et al. Understanding the Use of the Newcastle, PEDIG, and LACTOSE Control Scores Among Pediatric Ophthalmologists for Intermittent Exotropia[J]. J Pediatr Ophthalmol Strabismus, 2022, 25:1-8.
[22]
Zhong J, Deng D, Chen Z, et al. A novel dynamic random-dot stereopsis assessment to measure stereopsis in intermittent exotropia[J]. Ann Transl Med, 2021, 9(4): 308.
[23]
Dai S, Sun W, Xu H, et al. Effect of Applying Binocular Visual Training after Slanted Lateral Rectus Recession on Orthophoric Rate and Binocular Visual Function Recovery on Patients with Convergence Insufficiency-Type Intermittent Exotropia[J]. Evid Based Complement Alternat Med, 2021: 7202319.
[24]
张文辉,冯延琴. 手术结合视觉训练治疗间歇性外斜视患儿临床效果的Meta分析[J]. 临床医学研究与实践20216(10):34-37; 34-37, 44.
[25]
Kushner BJ, Does overcorrecting minus lens therapy for intermittent exotropia cause myopia?[J]. Arch Ophthalmol, 1999, 117: 638-642.
[26]
Tang SM, Chan RY, Bin Lin S, et al. Refractive Errors and Concomitant Strabismus: A Systematic Review and Meta-analysis[J]. Sci Rep, 2016, 6: 35177.
[27]
Li SM, Liu LR, Li SY, et al. Design, methodology and baseline data of a school-based cohort study in Central China: the Anyang Childhood Eye Study[J]. Ophthalmic Epidemiol, 2013, 20(6): 348-59.
[28]
Fu J, Li SM, Liu LR, et al. Prevalence of amblyopia and strabismus in a population of 7th-grade juniorhigh school students in Central China: the Anvang Childhood Eye Study (ACES)[J]. Ophthalmic epidlemiology, 2014, 21(3): 197-203.
[29]
任华明,李少敏,周楠. 间歇性外斜视致调节性近视(附3例报告)[J]. 中国斜视与小儿眼科杂志19964(1):20-22.
[30]
戴薇,付晶,洪洁,等. 间歇性外斜视合并近视患者调节功能的评价[J]. 中华眼视光学与视觉科学杂志202123(1):6-12.
[31]
Ha SG, Jang SM, Cho YA, et al. Clinical exhibition of increased accommodative loads for binocular fusion in patients with basic intermittent exotropia[J]. BMC Ophthalmol, 2016, 16: 77.
[32]
王小娟,赵堪兴. 间歇性外斜视的双眼调节功能[J]. 中华眼视光学与视觉科学杂志201315(8):471-474.
[33]
林惠玲,胡玉艳,徐昕頔,等. 间歇性外斜视的调节灵活度和调节反应[J]. 中华眼视光学与视觉科学杂志201820(5):265-268.
[34]
Schiavi C, Di Croce V, Primavera L, et al. Convergence, Accommodation, Fusion, and Stereopsis: What Keeps the Eyes Aligned in Intermittent Exotropia?[J]. Scientifica (Cairo), 2018: 9546979.
[35]
Shimojyo H, Kitaguchi Y, Asonuma S, et al. Age-related changes of phoria myopia in patients with intermittent exotropia[J]. Jpn J Ophthalmol, 2009, 53(1): 12-17.
[36]
姜方义. 间歇性外斜视患者调节功能与隐斜性近视漂移研究[J]. 中国实用眼科杂志201432(4):459-461.
[37]
杨素红,甘晓玲,任华明,等. 间歇性外斜视与儿童少年近视发展[J]. 中国斜视与小儿眼科杂志200816(1):1-4.
[38]
张薇. 儿童间歇性外斜视与近视屈光度增长的关系[J]. 包头医学院学报201834(8):43-44.
[39]
Moon Y, Kim JH, Lim HT. Difference in myopia progression between dominant and non-dominant eye in patients with intermittent exotropia[J]. Graefes Arch Clin Exp Ophthalmol, 2020, 258: 1327-1333.
[40]
Yang HK, Hwang JM. Decreased accommodative response in the nondominant eye of patients with intermittent exotropia[J]. Am J Ophthalmol, 2011, 151(1): 71-76.
[41]
Hasebe S, Nonaka F, Ohtsuki H. Accuracy of accommodation in heterophoric patients: testing an interaction model in a large clinical sample[J]. Ophthalmic Physiol Opt, 2005, 25(6): 582-591.
[42]
Horwood AM, Riddell PM. Evidence that convergence rather than accommodation controls intermittent distance exotropia[J]. Acta Ophthalmol, 2012, 90(2): e109-e117.
[43]
沈品呈,张杨,刘昱,等. 间歇性外斜视患者在不同注视条件下双眼调节反应差异的相关研究[J]. 中华眼科杂志201854(1):55-61.
[44]
Takase S, Yukumatsu S, Bingushi K. Local binocular fusion is involved in global binocular rivalry[J]. Vision Res, 2008, 48: 1798-803.
[45]
张璐,郭长梅. 间歇性外斜视患者调节和集合与屈光状态的关系[J]. 国际眼科纵览202145(6):556-560.
[46]
高帆,保金华,张芳,等. 间歇性外斜视手术对调节反应及调节微波动的影响[J]. 中华眼视光学与视觉科学杂志201820(9):536-540.
[47]
郭丽莉,王乐今. 儿童间歇性外斜视手术前后双眼调节功能变化[J]. 中华眼视光学与视觉科学杂志202123(11):840-844.
[48]
肖涵,刘虎. 间歇性外斜视的临床研究进展[J]. 中华眼科杂志202056(3):231-234.
[49]
Pediatric Eye Disease Investigator Group Writing Committee. Three-Year Observation of Children 3 to 10 Years of Age with Untreated Intermittent Exotropia[J]. Ophthalmology, 2019, 126(9): 1249-1260.
[50]
Cotter SA, Mohney BG, Chandler DL, et al. Three-year observation of children 12 to 35 months old with untreated intermittent exotropia[J]. Ophthalmic Physiol Opt, 2020, 40(2): 202-215.
[51]
Sung JY, Yang HK, Hwang JM, Comparison of surgery versus observation for small angle intermittent exotropia[J]. Sci Rep, 2020, 10(1): 4631.
[52]
Holmes JM, Hercinovic A, Melia BM, et al. Health-related quality of life in children with untreated intermittent exotropia and their parents[J]. J AAPOS, 2021, 25(2): 80.
[53]
Gramatikov BI. Detecting central fixation by means of artificial neural networks in a pediatric vision screener using retinal birefringencescanning[J]. Biomed Eng Online, 2017, 16(1): 52.
[54]
Chen Z, Fu H, Lo WL, et al. Strabismus recognition using eye-tracking data and convolutional neural networks[J]. J Healthc Eng, 2018: 7692198.
[55]
Lu J, Fan Z, Zheng C, et al. Automated strabismus detection for telemedicine applications[J]. ArXiv, 2018: 180902940.
[56]
Mao K, Yang Y, Guo C, et al. An artificial intelligence platform for the diagnosis and surgical planning of strabismus using corneal light-reflection photos[J]. Ann Transl Med, 2021, 9(5): 374.
[57]
许欣. 微创手术矫正间歇性外斜视的研究及人工智能手术量设计辅助系统的建立[D]. 北京:北京大学医学部,2021.
[1] 张梅芳, 谭莹, 朱巧珍, 温昕, 袁鹰, 秦越, 郭洪波, 侯伶秀, 黄文兰, 彭桂艳, 李胜利. 早孕期胎儿头臀长正中矢状切面超声图像的人工智能质控研究[J]. 中华医学超声杂志(电子版), 2023, 20(09): 945-950.
[2] 杨菲菲, 林锡祥, 陈亦新, 王秋霜, 张丽伟, 陈煦, 张梅青, 王淑华, 何昆仑. 基于深度学习的超声心动图自动识别节段性室壁运动异常的研究[J]. 中华医学超声杂志(电子版), 2023, 20(04): 424-429.
[3] 唐玮, 何融泉, 黄素宁. 深度学习在乳腺癌影像诊疗和预后预测中的应用[J]. 中华乳腺病杂志(电子版), 2023, 17(06): 323-328.
[4] 范帅华, 郭伟, 郭军. 基于机器学习的决策树算法在血流感染预后预测中应用现状及展望[J]. 中华实验和临床感染病杂志(电子版), 2023, 17(05): 289-293.
[5] 张辉, 蔡敏, 黄湘雅. 数字化技术和人工智能在上颌窦底提升术的临床应用[J]. 中华口腔医学研究杂志(电子版), 2023, 17(04): 244-252.
[6] 李晓阳, 刘柏隆, 周祥福. 大数据及人工智能对女性盆底功能障碍性疾病的诊断及风险预测[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 549-552.
[7] 胡博文, 戴英波. 泌尿外科机器人手术新趋势[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(04): 418-421.
[8] 邢晓伟, 刘雨辰, 赵冰, 王明刚. 基于术前腹部CT的卷积神经网络对腹壁切口疝术后复发预测价值[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 677-681.
[9] 邢晓伟, 刘雨辰, 王明刚. 人工智能技术在疝和腹壁外科领域的应用及展望[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(04): 390-393.
[10] 雷漫诗, 邓锶锶, 汪昕蓉, 黄锦彬, 向青, 熊安妮, 孟占鳌. 人工智能辅助压缩感知技术在上腹部T2WI压脂序列中的应用[J]. 中华肝脏外科手术学电子杂志, 2023, 12(05): 551-556.
[11] 韩冰, 顾劲扬. 深度学习神经网络在肝癌诊疗中的研究及应用前景[J]. 中华肝脏外科手术学电子杂志, 2023, 12(05): 480-485.
[12] 葛云鹏, 崔红元, 宋京海. 人工智能在原发性肝癌诊断、治疗及预后中的应用[J]. 中华肝脏外科手术学电子杂志, 2023, 12(04): 367-371.
[13] 王晓东, 汪恺, 葛昭, 丁忠祥, 徐骁. 计算机视觉技术在肝癌肝移植疗效提升中的研究进展[J]. 中华肝脏外科手术学电子杂志, 2023, 12(04): 361-366.
[14] 娜荷雅, 朱丹. 红光疗法在儿童近视眼防控中的研究进展[J]. 中华眼科医学杂志(电子版), 2023, 13(04): 252-256.
[15] 胡平, 鄢腾峰, 周海柱, 祝新根. 人工智能在非增强CT图像中颅内出血早期检出和血肿分割的研究进展[J]. 中华脑血管病杂志(电子版), 2023, 17(04): 410-416.
阅读次数
全文


摘要