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中华眼科医学杂志(电子版) ›› 2022, Vol. 12 ›› Issue (06) : 377 -381. doi: 10.3877/cma.j.issn.2095-2007.2022.06.011

综述

阿达木单抗在眼科临床应用的新进展
马嘉蹊1, 米倩倩2, 周义仁3, 王丹2,()   
  1. 1. 130021 长春中医药大学2020级眼科硕士研究生(2020年至今在吉林省人民医院眼科工作)
    2. 130021 长春,吉林省人民医院眼科
    3. 130021 长春中医药大学2019级眼科硕士研究生(2019年至2022年在吉林省人民医院眼科工作)
  • 收稿日期:2022-03-01 出版日期:2022-12-28
  • 通信作者: 王丹
  • 基金资助:
    吉林省药物临床合理使用促进项目(Y202115)

Advance on the clinical application of adalimumab in ophthalmology

Jiaxi Ma1, Qianqian Mi2, Yiren Zhou3, Dan Wang2,()   

  1. 1. Master′s degree 2020 major in ophthalmology), Changchun University of Traditional Chinese Medicine, Changchun 130021, China; Department of Ophthalmology, Jilin Province People′s Hospital (from 2020)
    2. Department of Ophthalmology, Jilin Province People′s Hospital, Changchun 130021, China
    3. Master′s degree 2019 major in ophthalmology, Changchun University of Traditional Chinese Medicine, Changchun 130021, China; Department of Ophthalmology, Jilin Province People′s Hospital (from 2019 to 2022)
  • Received:2022-03-01 Published:2022-12-28
  • Corresponding author: Dan Wang
引用本文:

马嘉蹊, 米倩倩, 周义仁, 王丹. 阿达木单抗在眼科临床应用的新进展[J/OL]. 中华眼科医学杂志(电子版), 2022, 12(06): 377-381.

Jiaxi Ma, Qianqian Mi, Yiren Zhou, Dan Wang. Advance on the clinical application of adalimumab in ophthalmology[J/OL]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2022, 12(06): 377-381.

阿达木单抗是一种注射用的生物治疗药物,其结构特点表现为人肿瘤坏死因子(TNF)的人源化单克隆抗体。阿达木单抗已先后在国家食品药品监督管理总局获批治疗类风湿关节炎、强直性脊柱炎,于2020年3月将非感染性葡萄膜炎纳入适应症内。近年来,阿达木单抗在临床应用中的作用越来越广泛。本文中笔者就阿达木单抗在眼科相关疾病应用的最新进展进行综述。

Adalimumab is a one of biological agents for injection. Its structure is characterized by humanized monoclonal antibody against human tumor necrosis factor (TNF). Adalimumab has been approved by the State Food and Drug Administration for the treatment of rheumatoid arthritis and ankylosing spondylitis. Non infectious uveitis was included in the indication in March 2020. Adalimumab is more and more widely used in clinical application. In this paper, the latest development of adalimumab in ophthalmic diseases was reviewed.

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