切换至 "中华医学电子期刊资源库"

中华眼科医学杂志(电子版) ›› 2019, Vol. 09 ›› Issue (06) : 321 -327. doi: 10.3877/cma.j.issn.2095-2007.2019.06.001

述评

重视青少年角膜塑形镜的规范验配、正确护理及并发症的治疗
孙璐1, 宋红欣1,()   
  1. 1. 100730 首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科研究所 北京市眼科学与视觉科学重点实验室
  • 收稿日期:2019-10-08 出版日期:2019-12-28
  • 通信作者: 宋红欣
  • 基金资助:
    首都卫生发展科研专项基金项目(首发2018-2z-1082)

Pay attention to myopia, orthokeratology, standard Ortho-K fitting procedure, complications

Lu Sun1, Hongxin Song1,()   

  1. 1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Beijing Ophthalmology & Visual Sciences Key Lab, Capital Medical University, Beijing 100730, China
  • Received:2019-10-08 Published:2019-12-28
  • Corresponding author: Hongxin Song
引用本文:

孙璐, 宋红欣. 重视青少年角膜塑形镜的规范验配、正确护理及并发症的治疗[J]. 中华眼科医学杂志(电子版), 2019, 09(06): 321-327.

Lu Sun, Hongxin Song. Pay attention to myopia, orthokeratology, standard Ortho-K fitting procedure, complications[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2019, 09(06): 321-327.

近年来,我国近视眼患病率不断上升,因为其普遍性和巨大的公共卫生成本,儿童近视眼和高度近视眼逐渐成为影响国民健康的公共卫生问题。角膜塑形镜(Ortho-K)是一种特殊的硬性隐形眼镜,在夜间佩戴以控制近视眼的发展,是目前公认的最有效控制近视眼的方法之一。在我国角膜塑形镜的应用已有10余年历史,因为Ortho-K镜的验配要求比较严格,同时控制效果也受到各种因素的影响。本文中笔者从目前Ortho-K镜的合理处方、验配流程、正确护理及并发症的处理等多个方面对Ortho-K镜的临床应用进行评述,以期实现长期健康的Ortho-K镜治疗。

In recent years, the prevalence of myopia has been rising in China. Because of its universality and huge public health costs, children′s myopia and high myopia have become public health problems affecting national health. The orthokeratology (Ortho-K) is a special design ridid contact lens which is worn at night to control the development of myopia and was recognized as one of the most effective way for myopic control. In China, the orthokeratology has been used widely for more than 10 years. Also, many domestic and foreign studies have confirmed the effect of the progression of myopia. However, Ortho-K fitting requirements are relatively strict, and the control effect is also affected by various factors. In this review, authors reviews the clinical application of orthokeratology from the current reasonable prescription and fitting methods of Ortho-K, correct nursing and treatment of complications, etc, which is of great benefit to practice long-term treatment plan for Ortho-K.

图1 戴隐形眼镜时所见的六类浸润性事件示意图 图A显示微生物角膜炎;图B显示接触性角膜溃疡;图C显示隐形眼镜致急性红眼;图D显示渗透性的角膜炎;图E显示无症状浸润性角膜炎;图F显示无症状的渗透。小黄点为弥漫性浸润区,大黄点为局灶性浸润区,绿点为角膜染色区。(引自Clinical Characterization of Corneal InfiltrativeEvents Observed with Soft Contact Lens Wear[71])
[1]
Flitcroft DI. The complex interactions of retinal, optical and environmental factors in myopia aetiology[J]. Prog Retin Eye Res, 2012, 31(6): 622-660.
[2]
Holden BA, Fricke TR, Wilson DA, et al. Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050[J]. Ophthalmology, 2016, 123(5): 1036-1042.
[3]
Hoogerheide J, Rempt F, Hoogenboom WP. Acquired myopia in young pilots[J]. Ophthalmologica, 1971, 163(4): 209-215.
[4]
Smith ER, Hung LF, Huang J. Relative peripheral hyperopic defocus alters central refractive development in infant monkeys[J]. Vision Res, 2009, 49(19): 2386-2392.
[5]
Irving EL, Callender MG, Sivak JG. Inducing ametropias in hatchling chicks by defocus-aperture effects and cylindrical lenses[J]. Vision Res, 1995, 35(9): 1165-1174.
[6]
Smith ER. Prentice Award Lecture 2010: A case for peripheral optical treatment strategies for myopia[J]. Optom Vis Sci, 2011, 88(9): 1029-1044.
[7]
Zhu Q, Liu Y, Tighe S, et al. Retardation of Myopia Progression by Multifocal Soft Contact Lenses[J]. Int J Med Sci, 2019, 16(2): 198-202.
[8]
Jones-Jordan LA, Sinnott LT, Manny RE, et al. Early childhood refractive error and parental history of myopia as predictors of myopia[J]. Invest Ophthalmol Vis Sci, 2010, 51(1): 115-121.
[9]
Rose KA, Morgan IG, Ip J, et al. Outdoor activity reduces the prevalence of myopia in children[J]. Ophthalmology, 2008, 115(8): 1279-1285.
[10]
Huang J, Wen D, Wang Q, et al. Efficacy Comparison of 16 Interventions for Myopia Control in Children: A Network Meta-analysis[J]. Ophthalmology, 2016, 123(4): 697-708.
[11]
Cho P, Cheung SW, Edwards M. The longitudinal orthokeratology research in children (LORIC) in Hong Kong: a pilot study on refractive changes and myopic control[J]. Curr Eye Res, 2005, 30(1): 71-80.
[12]
Hiraoka T, Kakita T, Okamoto F, et al. Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia: a 5-year follow-up study[J]. Invest Ophthalmol Vis Sci, 2012, 53(7): 3913-3919.
[13]
Swarbrick HA, Alharbi A, Watt K, et al. Myopia control during orthokeratology lens wear in children using a novel study design[J]. Ophthalmology, 2015, 122(3): 620-630.
[14]
Vander Veen DK, Kraker RT, Pineles SL, et al. Use of Orthokeratology for the Prevention of Myopic Progression in Children: A Report by the American Academy of Ophthalmology[J]. Ophthalmology, 2019, 126(4): 623-636.
[15]
Hotfiel T, Seil R, Bily W, et al. Nonoperative treatment of muscle injuries-recommendations from the GOTS expert meeting[J]. J Exp Orthop, 2018, 5(1): 24.
[16]
Swarbrick HA. Orthokeratology review and update[J]. Clin Exp Optom, 200689(3): 124-143.
[17]
Lipson MJ, Brooks MM, Koffler BH. The Role of Orthokeratology in Myopia Control: A Review[J]. Eye Contact Lens, 2018, 44(4): 224-230.
[18]
Adler IN, Wlodyga RJ, Rope SJ. The effects of pH on contact lens wearing[J]. J Am Optom Assoc, 1968, 39(11): 1000-1001.
[19]
Haque S, Fonn D, Simpson T, et al. Corneal and epithelial thickness changes after 4 weeks of overnight corneal refractive therapy lens wear, measured with optical coherence tomography[J]. Eye Contact Lens, 2004, 30(4): 189-193, 205-206.
[20]
Haque S, Fonn D, Simpson T, et al. Corneal refractive therapy with different lens materials, part 1: corneal, stromal, and epithelial thickness changes[J]. Optom Vis Sci, 2007, 84(4): 343-348.
[21]
Wen D, Huang J, Chen H, et al. Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis[J]. J Ophthalmol, 2015, 2015: 360806.
[22]
Si JK, Tang K, Bi HS, et al. Orthokeratology for myopia control: a meta-analysis[J]. Optom Vis Sci, 2015, 92(3): 252-257.
[23]
Donovan L, Sankaridurg P, Ho A, et al. Myopia progression rates in urban children wearing single-vision spectacles[J]. Optom Vis Sci, 2012, 89(1): 27-32.
[24]
Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, et al. Long-term Efficacy of Orthokeratology Contact Lens Wear in Controlling the Progression of Childhood Myopia[J]. Curr Eye Res, 2017, 42(5): 713-720.
[25]
Swarbrick HA, Alharbi A, Watt K, et al. Myopia control during orthokeratology lens wear in children using a novel study design[J]. Ophthalmology, 2015, 122(3): 620-630.
[26]
Chen C, Cheung SW, Cho P. Myopia control using toric orthokeratology (TO-SEE study)[J]. Invest Ophthalmol Vis Sci, 2013, 54(10): 6510-6517.
[27]
Charm J, Cho P. High myopia-partial reduction Ortho-K: a 2-year randomized study[J]. Optom Vis Sci, 2013, 90(6): 530-539.
[28]
Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, et al. Myopia control with orthokeratology contact lenses in Spain: refractive and biometric changes[J]. Invest Ophthalmol Vis Sci, 2012, 53(8): 5060-5065.
[29]
Hiraoka T, Kakita T, Okamoto F, et al. Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia: a 5-year follow-up study[J]. Invest Ophthalmol Vis Sci, 2012, 53(7): 3913-3919.
[30]
Walline JJ, Rah MJ, Jones LA. The Children's Overnight Orthokeratology Investigation (COOKI) pilot study[J]. Optom Vis Sci, 2004, 81(6): 407-413.
[31]
Parker KE, Leach NE. Orthokeratology: An Academic Perspective[J]. Eye Contact Lens, 2016, 42(1): 56-60.
[32]
Cho P, Boost M, Cheng R. Non-compliance and microbial contamination in orthokeratology[J]. Optom Vis Sci, 2009, 86(11): 1227-1234.
[33]
Mountford J, Pesudovs K. An analysis of the astigmatic changes induced by accelerated orthokeratology[J]. Clin Exp Optom, 2002, 85(5): 284-293.
[34]
Munnerlyn CR, Koons SJ, Marshall J. Photorefractive keratectomy: a technique for laser refractive surgery[J]. J Cataract Refract Surg, 1988, 14(1): 46-52.
[35]
Cho P, Lam AK, Mountford J, et al. The performance of four different corneal topographers on normal human corneas and its impact on orthokeratology lens fitting[J]. Optom Vis Sci, 2002, 79(3): 175-183.
[36]
Chui WS, Cho P. A comparative study of the performance of different corneal topographers on children with respect to orthokeratology practice[J]. Optom Vis Sci, 2005, 82(5): 420-427.
[37]
Kanamori K, Shoji K, Kinoshita N, et al. Complications of herpes zoster in children[J]. Pediatr Int, 2019, 19: 14025.
[38]
Liu YM, Xie P. The Safety of Orthokeratology-A Systematic Review[J]. Eye Contact Lens, 2016, 42(1): 35-42.
[39]
Cho P, Chui WS, Mountford J, et al. Corneal iron ring associated with orthokeratology lens wear[J]. Optom Vis Sci, 2002, 79(9): 565-568.
[40]
Cho P, Chui WS, Cheung SW. Reversibility of corneal pigmented arc associated with orthokeratology[J]. Optom Vis Sci, 2003, 80(12): 791-795.
[41]
Hiraoka T, Furuya A, Matsumoto Y, et al. Corneal iron ring formation associated with overnight orthokeratology[J]. Cornea, 2004, 23(8 Suppl): S78-S81.
[42]
Hiraoka T, Furuya A, Matsumoto Y, et al. Corneal iron ring formation associated with overnight orthokeratology[J]. Cornea, 2004, 23(8 Suppl): S78-S81.
[43]
Cheung SW, Cho P, Cheung A. White lesion in the corneal pigmented ring associated with orthokeratology[J]. Ophthalmic Physiol Opt, 2005, 25(3): 264-268.
[44]
Cheung SW, Cho P, Bron AJ, et al. Case report: the occurrence of fibrillary lines in overnight orthokeratology[J]. Ophthalmic Physiol Opt, 2006, 26(5): 525-531.
[45]
Lum E, Swarbrick H. Fibrillary lines in overnight orthokeratology[J]. Clin Exp Optom, 2007, 90(4): 299-302.
[46]
Poggio EC, Glynn RJ, Schein OD, et al. The incidence of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses[J]. N Engl J Med, 1989, 321(12): 779-783.
[47]
Lam DS, Houang E, Fan DS, et al. Incidence and risk factors for microbial keratitis in Hong Kong: comparison with Europe and North America[J]. Eye (Lond), 2002, 16(5): 608-618.
[48]
Cheng KH, Leung SL, Hoekman HW, et al. Incidence of contact-lens-associated microbial keratitis and its related morbidity[J]. Lancet, 1999, 354(9174): 181-185.
[49]
Seal DV, Kirkness CM, Bennett HG, et al. Population-based cohort study of microbial keratitis in Scotland: incidence and features[J]. Cont Lens Anterior Eye, 1999, 22(2): 49-57.
[50]
Schein OD, Glynn RJ, Poggio EC, et al. The relative risk of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses. A case-control study. Microbial Keratitis Study Group[J]. N Engl J Med, 1989, 321(12): 773-778.
[51]
Cheng KH, Leung SL, Hoekman HW, et al. Incidence of contact-lens-associated microbial keratitis and its related morbidity[J]. Lancet, 1999, 354(9174): 181-185.
[52]
Edwards K, Keay L, Naduvilath T, et al. Characteristics of and risk factors for contact lens-related microbial keratitis in a tertiary referral hospital[J]. Eye (Lond), 2009, 23(1): 153-160.
[53]
Fleiszig SM, Evans DJ. Pathogenesis of contact lens-associated microbial keratitis[J]. Optom Vis Sci, 2010, 87(4): 225-232.
[54]
Lin MC, Graham AD, Fusaro RE, et al. Impact of rigid gas-permeable contact lens extended wear on corneal epithelial barrier function[J]. Invest Ophthalmol Vis Sci, 2002, 43(4): 1019-1024.
[55]
Hsiao CH, Lin HC, Chen YF, et al. Infectious keratitis related to overnight orthokeratology[J]. Cornea, 200524(7): 783-788.
[56]
Madigan MC, Holden BA. Reduced epithelial adhesion after extended contact lens wear correlates with reduced hemidesmosome density in cat cornea[J]. Invest Ophthalmol Vis Sci, 199233(2): 314-323.
[57]
Mauger TF, Hill RM. Corneal epithelial healing under contact lenses. Quantitative analysis in the rabbit[J]. Acta Ophthalmol (Copenh), 1992, 70(3): 361-365.
[58]
Imayasu M, Petroll WM, Jester JV, et al. The relation between contact lens oxygen transmissibility and binding of Pseudomonas aeruginosa to the cornea after overnight wear[J]. Ophthalmology, 1994, 101(2): 371-388.
[59]
Cavanagh HD, Ladage P, Yamamoto K, et al. Effects of daily and overnight wear of hyper-oxygen transmissible rigid and silicone hydrogel lenses on bacterial binding to the corneal epithelium: 13-month clinical trials[J]. Eye Contact Lens, 2003, 29(1 Suppl): S14-S16, S26-S29, S192-S194.
[60]
Latkovic S, Nilsson SE. The effect of high and low Dk/L soft contact lenses on the glycocalyx layer of the corneal epithelium and on the membrane associated receptors for lectins[J]. CLAO J, 1997, 23(3): 185-191.
[61]
Ladage PM, Ren DH, Petroll WM, et al. Effects of eyelid closure and disposable and silicone hydrogel extended contact lens wear on rabbit corneal epithelial proliferation[J]. Invest Ophthalmol Vis Sci, 2003, 44(5): 1843-1849.
[62]
Wang Y, Nian H, Li Z, et al. Human encephalitis complicated with bilateral acute retinal necrosis associated with pseudorabies virus infection: A case report[J]. Int J Infect Dis, 2019, 25(89): 51-54.
[63]
Ren DH, Yamamoto K, Ladage PM, et al. Adaptive effects of 30-night wear of hyper-O(2) transmissible contact lenses on bacterial binding and corneal epithelium: a 1-year clinical trial[J]. Ophthalmology, 2002, 109(1): 27-40.
[64]
Ni M, Evans DJ, Hawgood S, et al. Surfactant protein D is present in human tear fluid and the cornea and inhibits epithelial cell invasion by Pseudomonas aeruginosa[J]. Infect Immun, 2005, 73(4): 2147-2156.
[65]
Kuroki Y, Takahashi M, Nishitani C. Pulmonary collectins in innate immunity of the lung[J]. Cell Microbiol, 2007, 9(8): 1871-1879.
[66]
McCormick CC, Hobden JA, Balzli CL, et al. Surfactant protein D in Pseudomonas aeruginosa keratitis[J]. Ocul Immunol Inflamm, 200715(5): 371-379.
[67]
Dart JK, Radford CF, Minassian D, et al. Risk factors for microbial keratitis with contemporary contact lenses: a case-control study[J]. Ophthalmology, 2008, 115(10): 1647-1654.
[68]
Sweeney DF, Jalbert I, Covey M, et al. Clinical characterization of corneal infiltrative events observed with soft contact lens wear[J]. Cornea, 2003, 22(5): 435-442.
[69]
Stapleton F, Keay L, Jalbert I, et al. The epidemiology of contact lens related infiltrates[J]. Optom Vis Sci, 200784(4): 257-272.
[70]
Lim C, Stapleton F, Mehta JS. Review of Contact Lens-Related Complications[J]. Eye Contact Lens, 2018, 44 (Suppl 2): S1-S10.
[71]
Sweeney DF, Jalbert I, Covey M, et al. Clinical characterization of corneal infiltrative events observed with soft contact lens wear[J]. Cornea, 2003, 22(5): 435-442.
[72]
Watt KG, Swarbrick HA. Trends in microbial keratitis associated with orthokeratology[J]. Eye Contact Lens, 2007, 33(6 Pt 2): 373-377, 382.
[73]
Chen KH, Kuang TM, Hsu WM. Serratia Marcescens corneal ulcer as a complication of orthokeratology[J]. Am J Ophthalmol, 2001, 132(2): 257-258.
[74]
Alkharashi M, Lindsley K, Law HA, et al. Medical interventions for acanthamoeba keratitis[J]. Cochrane Database Syst Rev, 2015, 24(2): D10792.
[75]
Takayama K, Kaburaki T, Takeuchi M. Development of Acute Retinal Necrosis in a Patient with Ocular Sarcoidosis: A Case Report[J]. Ocul Immunol Inflamm, 2019, 27(7): 1067-1070.
[76]
Claerhout I, Goegebuer A, Van Den Broecke C, et al. Delay in diagnosis and outcome of Acanthamoeba keratitis[J]. Graefes Arch Clin Exp Ophthalmol, 2004, 242(8): 648-653.
[77]
Tu EY, Joslin CE, Sugar J, et al. Prognostic factors affecting visual outcome in Acanthamoeba keratitis[J]. Ophthalmology, 2008, 115(11): 1998-2003.
[78]
Vaddavalli PK, Garg P, Sharma S, et al. Role of confocal microscopy in the diagnosis of fungal and acanthamoeba keratitis[J]. Ophthalmology, 2011, 118(1): 29-35.
[79]
Lehmann OJ, Green SM, Morlet N, et al. Polymerase chain reaction analysis of corneal epithelial and tear samples in the diagnosis of Acanthamoeba keratitis[J]. Invest Ophthalmol Vis Sci, 1998, 39(7): 1261-1265.
[80]
Dart JK, Saw VP, Kilvington S. Acanthamoeba keratitis: diagnosis and treatment update 2009[J]. Am J Ophthalmol, 2009, 148(4): 487-499.
[81]
Sun X, Zhang Y, Li R, et al. Acanthamoeba keratitis: clinical characteristics and management[J]. Ophthalmology, 2006113(3): 412-416.
[82]
Thebpatiphat N, Hammersmith KM, Rocha FN, et al. Acanthamoeba keratitis: a parasite on the rise[J]. Cornea, 2007, 26(6): 701-706.
[83]
Lau LI, Wu CC, Lee SM, et al. Pseudomonas corneal ulcer related to overnight orthokeratology[J]. Cornea, 2003, 22(3): 262-264.
[84]
Cope JR, Collier SA, Schein OD, et al. Acanthamoeba Keratitis among Rigid Gas Permeable Contact Lens Wearers in the United States, 2005 through 2011[J]. Ophthalmology, 2016, 123(7): 1435-1441.
[85]
Lam JS, Tan G, Tan DT, et al. Demographics and behaviour of patients with contact lens-related infectious keratitis in singapore[J]. Ann Acad Med Singapore, 2013, 42(10): 499-506.
[86]
Lipson MJ. Long-term clinical outcomes for overnight corneal reshaping in children and adults[J]. Eye Contact Lens, 2008, 34(2): 94-99.
[87]
Lo J, Kuo MT, Chien CC, et al. Microbial Bioburden of Orthokeratology Contact Lens Care System[J]. Eye Contact Lens, 2016, 42(1): 61-67.
[1] 金鑫, 谢卯, 刘芸, 杨操, 杨述华, 许伟华. 个性化股骨导向器辅助初次全髋关节置换的随机对照研究[J]. 中华关节外科杂志(电子版), 2023, 17(06): 780-787.
[2] 易晨, 张亚东, 董茜, 唐海阔, 刘志国. 应用骨盖技术拔除下颌低位骨性埋伏阻生第三磨牙的疗效观察[J]. 中华口腔医学研究杂志(电子版), 2023, 17(06): 424-429.
[3] 杜滨和, 徐楠, 杨云川, 崔培元. 5项改良衰弱指数预测胰十二指肠切除术近期预后的价值探讨[J]. 中华普通外科学文献(电子版), 2023, 17(06): 444-448.
[4] 李建美, 邓静娟, 杨倩. 两种术式联合治疗肝癌合并肝硬化门静脉高压的安全性及随访评价[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 41-44.
[5] 逄世江, 黄艳艳, 朱冠烈. 改良π形吻合在腹腔镜全胃切除消化道重建中的安全性和有效性研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 66-69.
[6] 杨体飞, 杨传虎, 陆振如. 改良无充气经腋窝入路全腔镜下甲状腺手术对喉返神经功能的影响研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 74-77.
[7] 陈垚, 徐伯群, 高志慧. 改良式中间上入路根治术治疗甲状腺癌的有效性安全性研究[J]. 中华普外科手术学杂志(电子版), 2023, 17(06): 619-622.
[8] 陈大敏, 曹晓刚, 曹能琦. 肥胖对胃癌患者手术治疗效果的影响研究[J]. 中华普外科手术学杂志(电子版), 2023, 17(06): 651-653.
[9] 曹智, 朱希望, 王尉, 张辉, 杨成林, 张小明. 经皮肾镜碎石取石术中不同肾盂内压力与围术期并发症相关性研究[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 616-620.
[10] 代格格, 杨丽, 胡媛媛, 周文婷. 手术室综合干预在老年腹股沟疝患者中的应用效果[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 759-763.
[11] 王敏, 蒋家斌, 李茂新. 预警宣教联合个性化疼痛管理对腹股沟疝手术患者的影响[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 764-767.
[12] 戴玮, 江桂林, 车兆平, 张姣, 王星星, 赵海涛. 无缝手术护理在腹股沟疝腹腔镜手术围手术期的应用效果[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 778-781.
[13] 叶晋生, 路夷平, 梁燕凯, 于淼, 冀祯, 贺志坚, 张洪海, 王洁. 腹腔镜下应用生物补片修补直肠术后盆底缺损的疗效[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 688-691.
[14] 袁伟, 张修稳, 潘宏波, 章军, 王虎, 黄敏. 平片式与填充式腹股沟疝修补术的疗效比较[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 697-701.
[15] 夏松, 姚嗣会, 汪勇刚. 经腹腹膜前与疝环充填式疝修补术治疗腹股沟疝的对照研究[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 702-705.
阅读次数
全文


摘要