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中华眼科医学杂志(电子版) ›› 2017, Vol. 07 ›› Issue (03) : 128 -132. doi: 10.3877/cma.j.issn.2095-2007.2017.03.006

所属专题: 经典病例 经典病例 文献

病例报告

青年性原发性眼内淋巴瘤一例
吕永川1, 陶勇2,()   
  1. 1. 河北省衡水市第四人民医院眼科
    2. 首都医科大学附属北京朝阳医院眼科
  • 收稿日期:2017-04-24 出版日期:2017-06-28
  • 通信作者: 陶勇
  • 基金资助:
    国家"863"高技术研究发展计划项目(2015AA020949)

Juvenile primary intraocular lymphoma: one case report

Yongchuan Lv1, Yong Tao2()   

  • Received:2017-04-24 Published:2017-06-28
  • Corresponding author: Yong Tao
引用本文:

吕永川, 陶勇. 青年性原发性眼内淋巴瘤一例[J]. 中华眼科医学杂志(电子版), 2017, 07(03): 128-132.

Yongchuan Lv, Yong Tao. Juvenile primary intraocular lymphoma: one case report[J]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2017, 07(03): 128-132.

表1 玻璃体液细胞因子检测结果
图1 患者眼底彩色照相图像 左眼黄斑区视网膜豹点状改变,视盘颞下方视网膜黄白色点状病灶,右眼底未见明显异常
图2 眼底自发荧光图像 A图示左眼后极部视网膜呈斑点状高荧光;B图示右眼眼底自发荧光,表现大致正常
图3 眼底荧光素血管造影图像 左眼黄斑区视网膜豹点状改变,对应的造影为低荧光区,与自发荧光相对应
图4 光学相干断层扫描图像视网膜色素上皮层结节状高反射信号
图5 患者2015年11月18日颅脑磁共振成像 未见异常
图6 患者2016年2月12日颅脑磁共振成像 显示双额占位性病变
[1]
Chan CC, Rubenstein JL, Coupland SE, et al. Primary vitreoretinal lymphoma: a report from an International Primary Central Nervous System Lymphoma Collaborative Group symposium[J]. Oncologist, 2011, 16(11):1589-1599.
[2]
Faia LJ, Chan CC. Primary Intraocular Lymphoma[J]. Arch Pathol Lab Med, 2009, 133(8):1228-1232.
[3]
刘忆南,魏文斌. 眼内及眼附属器淋巴瘤的组织病理学表现[J]. 国际眼科纵览,2015,39(6):418-422.
[4]
周旻,江睿,张艳琼,等. 原发性眼内淋巴瘤13例[J]. 中华眼底病杂志,2012,28(3):245-248.
[5]
Chan CC, Fisson S, Bodaghi B. The future of primary intraocular lymphoma (retinal lymphoma)[J]. Ocul Immunol Inflamm, 2009, 17(6):375-379.
[6]
Cao X, Shen D, Callanan DG, et al. Diagnosis of systemic metastatic retinal lymphoma[J]. Acta Ophthalmologica, 2011, 89(2):149-154.
[7]
Hong JT, Chae JB, Lee JY, et al. Ocular involvement in patients with primary CNS lymphoma[J]. Journal of Neuro-Oncology, 2011, 102(1):139-145.
[8]
Faia LJ, Chan CC. Primary intraocular lymphoma[J]. Annals of Ophthalmology, 2001, 33(3):233-236.
[9]
Hwang CS, Yeh S, Bergstrom CS. Diagnostic vitrectomy for primary intraocular lymphoma: when, why, how?[J]. Int Ophthalmol Clin, 2014, 54(2):155-171.
[10]
李孟达,叶俊杰. 原发性眼内淋巴瘤的研究进展[J]. 中华眼科杂志,2015,51(10):795-800.
[11]
Coupland SE, Chan CC, Smith J. Pathophysiology of retinal lymphoma[J]. Ocul Immunol Inflamm, 2009, 17(4):227-237.
[12]
Hochberg FH, Miller DC. Primary central nervous system lymphoma[J]. J Neurosurg, 1988, 68(6):835-853.
[13]
王敏,张美芬. 原发性眼内淋巴瘤[J]. 中华眼底病杂志,2015,31(2):208-211.
[14]
Mochizuki M, Singh AD. Epidemiology and clinical features of intraocular lymphoma[J]. Ocul Immunol Inflamm, 2009, 17(2):69-72.
[15]
Davis JL. Intraocular lymphoma: a clinical perspective[J]. Eye(Lond), 2013, 27(2):153-162.
[16]
Zamora DO, Riviere M, Choi D, et al. Proteomic profiling of human retinal and choroidal endothelial cells reveals molecular heterogeneity related to tissue of origin[J]. Mol Vis, 2007, 13(233):2058-2065.
[17]
Sauer TC, Meyers SM, Shen DF, et al. Primary intraocular (retinal) lymphoma after ocular toxoplasmosis[J]. Retin Cases Brief Rep, 2010, 4(2):160-163.
[18]
Malumbres R, Davis J, Ruiz P, et al. Somatically mutated immunoglobulin IGHV@ genes without intraclonal heterogeneity indicate a postgerminal centre origin of primary intraocular diffuse large B-cell lymphomas[J]. Br J Haematol, 2007, 138(6):749-755.
[19]
Kim YK, Kim HJ, Woo KI, et al. Intraocular lymphoma after cardiac transplantation: magnetic resonance imaging findings[J]. Korean J Radiol, 1900, 14(1):122-125.
[20]
Goto H, Mochizuki M, Yamaki K, et al. Epidemiological survey of intraocular inflammation in Japan[J]. Jpn J Ophthalmol, 2007, 51(1):41-44.
[21]
Vollmer L. The diagnosis and management of ocular lymphoma[J]. Optom Vis Sci, 2013, 90(2):56-62.
[22]
Casady M, Faia L, Nazemzadeh M, et a1. Fundus autofluorescence patterns in primary intraocular lymphoma[J]. Retina, 2014, 34(2):366-372.
[23]
Velez G, Chan CC, Csaky KG. Fluorescein angiographic findings in primary intraocular lymphoma[J]. Retina, 2002, 22(1):37-43.
[24]
Egawa M, Mitamura Y, Hayashi Y, et al. Spectral-domain optical coherence tomographic and fundus autofluorescence findings in eyes with primary intraocular lymphoma[J]. Clinical Ophthalmology, 2014, 8(default):335-341.
[25]
Egawa M, Mitamura Y, Hayashi Y, et al. Changes of fundus autofluorescence and spectral-domain optical coherence tomographic findings after treatment of primary intraocular lymphoma[J]. Journal of Ophthalmic Inflammation and Infection, 2014, 4(1):7.
[26]
Jang HS, Sepah YJ, Sophie R, et al. Longitudinal spectral domain optical coherence tomography changes in eyes with intraocular lymphoma[J]. J Ophthalmic Inflamm Infect, 2013, 3(1):59.
[27]
Coupland SE, Bechrakis NE, Anastassiou G, et al. Evaluation of vitrectomy specimens and chorioretinal biopsies in the diagnosis of primary intraocular lymphoma in patients with Masquerade syndrome[J]. Graefe′s Archive for Clinical and Experimental Ophthalmology, 2003, 241(10):860-870.
[28]
Kanavi MR, Soheilian M, Hosseini SB, et al. 25-gauge transconjunctival diagnostic vitrectomy in suspected cases of intraocular lymphoma: a case series and review of the literature[J]. Int J Ophthalmol, 2014, 7(3):577-581.
[29]
Yeh S, Weichel ED, Faia LJ, et al. 25-gauge transconjunctival sutureless vitrectomy for the diagnosis of intraocular lymphoma[J]. Br J Ophthalmol, 2010, 94(5):633-638.
[30]
Cassoux N, Giron A, Bodaghi B, et al. IL-10 Measurement in Aqueous Humor for Screening Patients with Suspicion of Primary Intraocular Lymphoma[J]. Invest Ophthalmol Vis Sci, 2007, 48(7):3253-2359.
[31]
Whitcup SM, Starkvancs V, Wittes RE, et al. Association of interleukin 10 in the vitreous and cerebrospinal fluid and primary central nervous system lymphoma[J]. Arch Ophthalmol, 1997, 115(9):1157-1160.
[32]
Sugita S, Takase H, Sugamoto Y, et al. Diagnosis of intraocular lymphoma by polymerase chain reaction analysis and cytokine profiling of the vitreous fluid[J]. Japanese Journal of Ophthalmology, 2009, 53(3):209-214.
[33]
Kimura K, Usui Y, Goto H. Clinical features and diagnostic significance of the intraocular fluid of 217 patients with intraocular lymphoma[J]. Japanese Journal of Ophthalmology, 2012, 56(4):383-389.
[34]
Smith JR, Rosenbaum JT, Wilson DJ, et al. Role of intravitreal methotrexate in the management of primary central nervous system lymphoma with ocular involvement[J]. Ophthalmology, 2002, 109(9):1709-1716.
[35]
DeAngelis LM. Primary central nervous system lymphomas[J]. Curr Treat Options in Oncol, 2001, 2(4):309-318.
[36]
Valluri S, Moorthy RS, Khan A, et al. Combination treatment of intraocular lymphoma[J]. Retina, 1995, 15(2):125.
[37]
Mason JO, Fischer DH. Intrathecal chemotherapy for recurrent central nervous system intraocular lymphoma[J]. Ophthalmology, 2003, 110(6):1241-1244.
[38]
Soussain C, Merle-Béral H, Reux I, et al. A single-center study of 11 patients with intraocular lymphoma treated with conventional chemotherapy followed by high-dose chemotherapy and autologous bone marrow transplantation in 5 cases[J]. Leukemia & Lymphoma, 1996, 23(3-4):339.
[39]
Helbig H, Cerny T, de Smet MD. Intravitreal chemotherapy for intraocular lymphoma[J]. Der Ophthalmologe, 2003, 100(2):145-149.
[40]
Jahnke K, Bechrakis NE, Coupland SE, et al. Treatment of primary intraocular lymphoma with oral trofosfamide: report of two cases and review of the literature[J]. Graefe′s Archive for Clinical and Experimental Ophthalmology, 2004, 242(9):771.
[41]
Feugier P, Virion JM, Tilly H, et al. Incidence and risk factors for central nervous system occurrence in elderly patients with diffuse large-B-cell lymphoma: influence of rituximab[J]. Annals of Oncology, 2004, 15(1):129.
[42]
Ferreri AJ, Blay JY, Reni M, et al. Relevance of intraocular involvement in the management of primary central nervous system lymphomas[J]. Annals of Oncology, 2002, 13(4):531-538.
[43]
Buggage RR, Chan CC, Nussenblatt RB. Ocular manifestations of central nervous system lymphoma[J]. Current Opinion in Oncology, 2001, 13(13):137-142.
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