基于国际干眼新共识的干眼研究进展

doi:10.3877/cma.j.issn.2095-2007.2018.01.006

干眼是目前除屈光不正外最常见的眼部疾病，其主要特征是泪膜不稳定和高渗透的恶性循环所导致的眼表炎症、损伤及眼部异物感。中度至重度的干眼会伴有明显的疼痛，导致患者生活质量下降，甚至产生抑郁等心理问题。据调查，门诊干眼患者占全部眼科就诊患者的30%以上，环境污染、视频终端的使用习惯不良及生活节奏的加快使干眼患者群体不断增加，且呈低龄化发展趋势。干眼概念自1995年提出至今，其科学研究已成为眼科最热门的领域之一。2007年，国际泪膜和眼表协会在干眼工作组(DEWS)会议上发布干眼系列共识DEWSⅠ。十年间，有关干眼的各方面研究均有了显著的进展，2017年，国际泪膜和眼表协会DEWS第二次会议发布了干眼新共识DEWSⅡ。本文中笔者基于两次报告围绕干眼的研究进展进行综述。

关键词: 干眼, 干眼工作组第二次会议, 新共识

Dry eye has become the most common eye disease besides ametropia. Its main feature is tear film instability and high permeability of the vicious cycle caused by ocular surface inflammation, injury and eye foreign body sensation. Moderate to severe dry eyes will be accompanied by obvious pain, resulting in a decline in the quality of life and even psychological problems such as depression. Environmental pollution, the poor use of video terminal and the quickening of the rhythm of life make the population of dry eye increase continuously, and the incidence of dry eye to the lower age. Since the concept of dry eye was put forward in 1995, its scientific research has become one of the most popular fields in ophthalmology. In 2007, the international tear film and eye Watch Association issued a first edition of the first edition of the dry eye series on the dry eye group (DEWS) meeting. Ten years, significant progress has been made in all aspects of dry eye research. In 2017, the DEWSⅡ report was published by the international tear film and eye Watch Association DEWS second meeting. The author makes a review of research progress on dry eye based on DEWSⅠ and DEWSⅡ .

Key words: Dry eye, Dry Eye WorkshopⅡ, Research progress

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Development of dry eye research based on international dry eye new consensus

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Development of dry eye research based on international dry eye new consensus