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中华眼科医学杂志(电子版) ›› 2026, Vol. 16 ›› Issue (02) : 97 -100. doi: 10.3877/cma.j.issn.2095-2007.2026.02.006

病例报告

以孤立性动眼神经麻痹首发的颅底脊索瘤1例
王姗姗1, 叶盛铭1, 叶亲颖2,()   
  1. 1524023 广东省湛江市,广东医科大学附属医院眼科
    2524023 广东省湛江市,广东医科大学附属第二医院眼科
  • 收稿日期:2025-10-30 出版日期:2026-04-28
  • 通信作者: 叶亲颖
  • 基金资助:
    广东省自然科学基金项目(2025A1515012417)

One case of chordoma in the skull base with isolated oculomotor nerve palsy

Shanshan Wang, Shengming Ye, Qinying Ye()   

  • Received:2025-10-30 Published:2026-04-28
  • Corresponding author: Qinying Ye
引用本文:

王姗姗, 叶盛铭, 叶亲颖. 以孤立性动眼神经麻痹首发的颅底脊索瘤1例[J/OL]. 中华眼科医学杂志(电子版), 2026, 16(02): 97-100.

Shanshan Wang, Shengming Ye, Qinying Ye. One case of chordoma in the skull base with isolated oculomotor nerve palsy[J/OL]. Chinese Journal of Ophthalmologic Medicine(Electronic Edition), 2026, 16(02): 97-100.

图1 患者治疗前第一眼位及各方位眼球运动彩色照相 图1A~1E示患者第一眼位及各方位眼球运动照相  图2 患者颅底电子计算机断层扫描三维重建影像 图2A示平扫模式下鞍区可见不规则软组织占位(大小约22 mm×19 mm×25 mm),内部可见散在高密度影,可见邻近骨质破坏;图2B示增强模式下肿瘤病灶明显强化,鼻咽右侧壁及顶后壁软组织增厚;病灶侵犯海绵窦
图3 鼻咽-颈部磁共振成像平扫+增强图像 图3A示轴位T2WI,可见鼻咽双侧顶壁、顶后壁及右侧壁增厚并见软组织肿物,呈异常高信号,增强后不均匀强化,内见不规则坏死区;图3B~3C示轴位T1WI增强,可见肿瘤病灶明显强化,右侧海绵窦受侵,颅底骨质破坏;图3D示矢状位T1WI扫描  图4 电子鼻咽镜检查显微照像 图4A示鼻咽顶后壁见粘膜结节样隆起,大小约1.0 cm×1.0 cm,表面光滑,质地硬。双侧鼻咽侧壁粘膜光滑;图4B示右侧咽隐窝变浅;图4C示左侧圆枕粘膜光滑;图4D示左侧隐窝未见异常
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