| [1] |
Taiyab A, Holms J, West－Mays JA. Beta－catenin/Smad3 interaction regulates transforming growth factor－beta－induced epithelial to mesenchymal transition in the lens[J]. Int J Mol Sci, 2019, 20(9): 2078.
|
| [2] |
Zhang C, Guo Q, Tong Z, et al. Thin film nanoarchitectonics of layer－by－layer assembly with reduced graphene oxide on intraocular lens for photothermal therapy of posterior capsular opacification[J]. J Colloid Interface Sci, 2022, 619: 348－358.
|
| [3] |
Kubo E, Shibata T, Singh DP, et al. Roles of TGF beta and FGF signals in the lens: tropomyosin regulation for posterior capsule opacity[J]. Int J Mol Sci, 2018, 19(10): 3093.
|
| [4] |
Nibourg LM, Gelens E, Kuijer R, et al. Prevention of posterior capsular opacification[J]. Exp Eye Res, 2015, 136: 100－115.
|
| [5] |
Li H, Yuan X, Li J, et al. Implication of Smad2 and Smad3 in transforming growth factor－β－induced posterior capsular opacification of human lens epithelial cells[J]. Current Eye Research, 2014, 40(4): 386－397.
|
| [6] |
Xie W, Yu Q, Wang L, et al. Toll－like receptor 3 gene regulates cataract－related mechanisms via the Jagged－1/Notch signaling pathway[J]. Bioengineered, 2022, 13(6): 14357－14367.
|
| [7] |
Chen X, Ye S, Xiao W, et al. ERK1/2 pathway mediates epithelial－mesenchymal transition by cross－interacting with TGFbeta/Smad and Jagged/Notch signaling pathways in lens epithelial cells[J]. Int J Mol Med, 2014, 33(6): 1664－1670.
|
| [8] |
Nam MH, Nagaraj RH. Matrix－bound AGEs enhance TGFbeta2－mediated mesenchymal transition of lens epithelial cells via the noncanonical pathway: implications for secondary cataract formation[J]. Biochem J, 2018, 475(8): 1427－1440.
|
| [9] |
Yao J, Yang W, Liu Y, et al. Dexamethasone inhibits TGF－beta2－induced migration of human lens epithelial cells: implications for posterior capsule opacification prevention[J]. Mol Med Rep, 2012, 5(6): 1509－1513.
|
| [10] |
Chen X, Xiao W, Chen W, et al. The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial－mesenchymal transition of lens epithelial cells[J]. Cell Death Dis, 2013, 4(10): e884.
|
| [11] |
Ning J, Ma X, Long C, et al. Anti－tumor drug THZ1 suppresses TGFbeta2－mediated EMT in lens epithelial cells via Notch and TGFbeta/Smad signaling pathway[J]. J Cancer, 2019, 10(16): 3778－3788.
|
| [12] |
Costello MJ, Brennan LA, Basu S, et al. Autophagy and mitophagy participate in ocular lens organelle degradation[J]. Exp Eye Res, 2013, 116: 141－150.
|
| [13] |
Chandler HL, Gervais KJ, Lutz EA, et al. Cyclosporine A prevents ex vivo PCO formation through induction of autophagy－mediated cell death[J]. Exp Eye Res, 2015, 134: 63－72.
|
| [14] |
Li H, Song H, Yuan X, et al. miR－30a reverses TGF－beta2－induced migration and EMT in posterior capsular opacification by targeting Smad2[J]. Mol Biol Rep, 2019, 46(4): 3899－3907.
|
| [15] |
Zhou W, Xu J, Wang C, et al. MiR－23b－3p regulates apoptosis and autophagy via suppressing SIRT1 in lens epithelial cells[J]. J Cell Biochem, 2019, 120(12): 19635－19646.
|
| [16] |
Sun Y, Xiong L, Wang X, et al. Autophagy inhibition attenuates TGF－beta2－induced epithelial－mesenchymal transition in lens epithelial cells[J]. Life Sci, 2021, 265: 118741.
|
| [17] |
Li J, Yu J, Huang W, et al. Extracellular HSP90 promotes differentiation of lens epithelial cells to fiber cells by activating LRP1－YAP－PROX1 axis[J]. FASEB J, 2023, 37(2): e22783.
|
| [18] |
刘含若，袁博伟，安莹，等. 莱菔硫烷激发的细胞自噬潮对离体人晶状体囊上细胞增生的抑制作用[J]. 中华实验眼科杂志，2017, 35(3): 226－232.
|
| [19] |
Wang Y, Li W, Zang X, et al. MicroRNA－204－5p regulates epithelial－to－mesenchymal transition during human posterior capsule opacification by targeting SMAD4[J]. Invest Ophthalmol Vis Sci, 2013, 54(1): 323－332.
|
| [20] |
Dong N, Xu B, Benya SR, et al. MiRNA－26b inhibits the proliferation, migration, and epithelial－mesenchymal transition of lens epithelial cells[J]. Mol Cell Biochem, 2014, 396(1－2): 229－238.
|
| [21] |
Dong N, Tang X, Xu B. MiRNA－181a inhibits the proliferation, migration, and epithelial－mesenchymal transition of lens epithelial cells[J]. Invest Ophthalmol Vis Sci, 2015, 56(2): 993－1001.
|
| [22] |
Liu B, Sun J, Lei X, et al. MicroRNA－486－5p suppresses TGF－beta2－induced proliferation, invasion and epithelial－mesenchymal transition of lens epithelial cells by targeting Smad2[J]. J Biosci, 2017, 42(4): 575－584.
|
| [23] |
Han R, Hao P, Wang L, et al. MicroRNA－34a inhibits epithelial－mesenchymal transition of lens epithelial cells by targeting Notch1[J]. Experimental Eye Research, 2019, 185: 107684.
|
| [24] |
Economou MA, Wu J, Vasilcanu D, et al. Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin－like growth factor－1 receptor[J]. Acta Ophthalmol, 2008, 86(4): 42－49.
|
| [25] |
Li X, Sun M, Cheng A, et al. LncRNA GAS5 regulates migration and epithelial－to－mesenchymal transition in lens epithelial cells via the miR－204－3p/TGFBR1 axis[J]. Lab Invest, 2022, 102(4): 452－460.
|
| [26] |
Wang J, Zhang J, Xiong Y, et al. TGF－beta regulation of microRNA miR－497－5p and ocular lens epithelial cell mesenchymal transition[J]. Sci China Life Sci, 2020, 63(12): 1928－1937.
|
| [27] |
Xiong L, Sun Y, Huang J, et al. Long non－coding RNA H19 prevents lens fibrosis through maintaining lens epithelial cell phenotypes[J]. Cells, 2022, 11(16): 2559.
|
| [28] |
Wang H, Zheng G. Circ－GGA3 promotes the biological functions of human lens epithelial cells depending on the regulation of miR－497－5p/SMAD4 axis[J]. Biochem Biophys Res Commun, 2022, 598: 62－68.
|
| [29] |
Guo M, Su F, Chen Y, et al. Interfering Hsa_circRNA_0060640 suppresses TGF－beta2－induced proliferation, motility and EMT in human lens epithelium cells by targeting miR－214－3p and collagen type I alpha2 chain[J]. Curr Eye Res, 2022, 47(5): 735－746.
|
| [30] |
Huang P, Hu Y, Duan Y. TGF－beta2－induced circ－PRDM5 regulates migration, invasion, and EMT through the miR－92b－3p/COL1A2 pathway in human lens epithelial cells[J]. J Mol Histol, 2022, 53(2): 309－320.
|
| [31] |
Jing R, Hu C, Qi T, et al. FILIP1L－mediated cell apoptosis, epithelial－mesenchymal transition and extracellular matrix synthesis aggravate posterior capsular opacification[J]. Life Sci, 2021, 286: 120061.
|
| [32] |
Ma B, Yang L, Jing R, et al. Effects of interleukin－6 on posterior capsular opacification[J]. Exp Eye Res, 2018, 172: 94－103.
|
| [33] |
Jiang J, Shihan MH, Wang Y, et al. Lens epithelial cells initiate an inflammatory response following cataract surgery[J]. Invest Ophthalmol Vis Sci, 2018, 59(12): 4986－4997.
|
| [34] |
Awasthi N, Wang－Su ST, Wagner BJ. Downregulation of MMP－2 and －9 by proteasome inhibition: a possible mechanism to decrease LEC migration and prevent posterior capsular opacification[J]. Invest Ophthalmol Vis Sci, 2008, 49(5): 1998－2003.
|
| [35] |
Mclean SM, Mathew MR, Kelly JB, et al. Detection of integrins in human cataract lens epithelial cells and two mammalian lens epithelial cell lines[J]. Br J Ophthalmol, 2005, 89(11): 1506－1509.
|
| [36] |
Ma B, Ni N, Shao W, et al. Bit1 is involved in regulation between integrin and TGFbeta signaling in lens epithelial cells[J]. Cell Cycle, 2022, 21(21): 2283－2297.
|
| [37] |
Aose M, Matsushima H, Mukai K, et al. Influence of intraocular lens implantation on anterior capsule contraction and posterior capsule opacification[J]. J Cataract Refract Surg, 2014, 40(12): 2128－2133.
|
| [38] |
Jaitli A, Roy J, Chatila A, et al. Role of fibronectin and IOL surface modification in IOL: lens capsule interactions[J]. Exp Eye Res, 2022, 221: 109135.
|
| [39] |
Mastromonaco C, Balazsi M, Coblentz J, et al. Histopathological analysis of residual lens cells in capsular opacities after cataract surgery using objective software[J]. Indian J Ophthalmol, 2022, 70(5): 1617－1625.
|
| [40] |
Versura P, Torreggiani A, Cellini M, et al. Adhesion mechanisms of human lens epithelial cells on 4 intraocular lens materials[J]. J Cataract Refract Surg, 1999, 25(4): 527－533.
|
| [41] |
Grzybowski A, Zemaitiene R, Markeviciute A, et al. Should we abandon hydrophilic intraocular lenses？[J]. Am J Ophthalmol, 2022, 237: 139－145.
|
| [42] |
Huang Y, Xie L. Delayed postoperative opacification of foldable hydrophilic acrylic intraocular lenses[J]. J Biomed Mater Res B Appl Biomater, 2011, 96(2): 386－391.
|
| [43] |
Hoehn R, Mirshahi A, Hoffmann EM, et al. Distribution of intraocular pressure and its association with ocular features and cardiovascular risk factors: the Gutenberg Health Study[J]. Ophthalmology, 2013, 120(5): 961－968.
|
| [44] |
Wang E, Reid B, Lois N, et al. Electrical inhibition of lens epithelial cell proliferation: an additional factor in secondary cataract？[J]. FASEB J, 2005, 19(7): 842－844.
|
| [45] |
Chaudhry M, Baisakhiya S, Bhatia MS. A rare complication of Nd－YAG capsulotomy: propionibacterium acnes endopthalmitis[J]. Nepal J Ophthalmol, 2011, 3(1): 80－82.
|
| [46] |
Zhang X, Lai K, Li S, et al. Drug－eluting intraocular lens with sustained bromfenac release for conquering posterior capsular opacification[J]. Bioact Mater, 2022, 9: 343－357.
|
| [47] |
Li Q, Liu S, Yang G, et al. Naringenin inhibits autophagy and epithelial－mesenchymal transition of human lens epithelial cells by regulating the Smad2/3 pathway[J]. Drug Dev Res, 2022, 83(2): 389－396.
|
| [48] |
Wang L, Tian Y, Shang Z, et al. Metformin attenuates the epithelial－mesenchymal transition of lens epithelial cells through the AMPK/TGF－beta/Smad2/3 signalling pathway[J]. Exp Eye Res, 2021, 212: 108763.
|
| [49] |
Sugiyama Y, Nakazawa Y, Sakagami T, et al. Capsaicin attenuates TGFbeta2－induced epithelial－mesenchymal－transition in lens epithelial cells in vivo and in vitro[J]. Exp Eye Res, 2021, 213: 108840.
|
| [50] |
Huai B, Huang C, Hu L. Curcumin suppresses TGF－beta2－induced proliferation, migration, and invasion in lens epithelial cells by targeting KCNQ1OT1/miR－377－3p/COL1A2 axis in posterior capsule opacification[J]. Curr Eye Res, 2022, 47(5): 715－726.
|
| [51] |
Wang Z, Gao R, Shi Q, et al. Inhibitory effects of NO－fluvastatin on proliferation of human lens epithelial cells in vitro by modulating cell cycle regulatory proteins[J]. J Huazhong Univ Sci Technolog Med Sci, 2008, 28(5): 588－591.
|
| [52] |
Zhang RP, Xie ZG. Research progress of drug prophylaxis for lens capsule opacification after cataract surgery[J]. J Ophthalmol, 2020: 2181685.
|
| [53] |
Wang R, Xia J, Tang J, et al. Surface modification of intraocular lens with hydrophilic poly (sulfobetaine methacrylate) brush for posterior capsular opacification prevention[J]. J Ocul Pharmacol Ther, 2021, 37(3): 172－180.
|
| [54] |
Seo Y, Kim S, Lee HS, et al. Femtosecond laser induced nano－textured micropatterning to regulate cell functions on implanted biomaterials[J]. Acta Biomater, 2020, 116: 138－148.
|
| [55] |
Hazra S, Palui H, Vemuganti GK. Comparison of design of intraocular lens versus the material for PCO prevention[J]. Int J Ophthalmol, 2012, 5(1): 59－63.
|
| [56] |
Teng H, Zhang H, Tian F, et al. The study of cyclosporin A modified intraocular lens preventing posterior capsular opacification in rabbit eyes[J]. Zhonghua Yan Ke Za Zhi, 2016, 52(2): 110－116.
|
| [57] |
Lu D, Han Y, Liu D, et al. Centrifugally concentric ring－patterned drug－loaded polymeric coating as an intraocular lens surface modification for efficient prevention of posterior capsular opacification[J]. Acta Biomater, 2022, 138: 327－341.
|
| [58] |
Kassumeh SA, Wertheimer CM, Von Studnitz A, et al. Poly (lactic－co－glycolic) acid as a slow－release drug－carrying matrix for methotrexate coated onto intraocular lenses to conquer posterior capsule opacification[J]. Curr Eye Res, 2018, 43(6): 702－708.
|
| [59] |
Sun CB, Teng WQ, Cui JT, et al. The effect of anti－TGF－beta2 antibody functionalized intraocular lens on lens epithelial cell migration and epithelial－mesenchymal transition[J]. Colloids Surf B Biointerfaces, 2014, 113: 33－42.
|
| [60] |
Wormstone IM, Tamiya S, Eldred JA, et al. Characterisation of TGF－beta2 signalling and function in a human lens cell line[J]. Exp Eye Res, 2004, 78(3): 705－714.
|
| [61] |
Wang D, Guo D, Bi H, et al. Zinc oxide nanoparticles inhibit Ca2+－ATPase expression in human lens epithelial cells under UVB irradiation[J]. Toxicol In Vitro, 2013, 27(8): 2117－2126.
|
| [62] |
Liu D, Wu Q, Chen W, et al. Nanoporous gold ring－integrated photothermal intraocular lens for active prevention of posterior capsular opacification[J]. Small, 2022, 18(34): e2201098.
|
| [63] |
Mao YY, Li M, Wang JD, et al. NIR－triggered drug delivery system for chemo－photothermal therapy of posterior capsule opacification[J]. J Control Release, 2021, 339: 391－402.
|
| [64] |
Hong Y, Fang Q, Bai T, et al. Cascade reaction triggering and photothermal AuNPs@MIL MOFs doped intraocular lens for enhanced posterior capsular opacification prevention[J]. J Nanobiotechnology, 2023, 21(1): 134.
|
| [65] |
Zhang D, Zhu H, Yu X, et al. Blue light attenuates TGF－beta2－induced epithelial－mesenchymal transition in human lens epithelial cells via autophagy impairment[J]. BMC Ophthalmol, 2022, 22(1): 456.
|